Cyst fluid from women with gross cystic breast disease was found to contain protease activity when assayed against [14C]albumin. At least six different proteases were detected when the fluid was fractionated by a combination of S-300 Sephacel, hydroxylapatite, and DEAE-Sephacel chromatographic techniques. The distribution of the proteases appeared to be related to the ionic composition of the f...

The gross alpha (α) and beta (β) activities and trace heavy elemental concentrations have been determined in Single Super Phosphate (SSP) and Nitrogen Phosphorous Potassium (NPK) fertilizers samples used for agricultural purposes in Nigeria. Cultivated farm soil samples from two regions (north and south) in the country and samples of phosphate rocks were also analyzed for gross α and β radioact...

background: tea is one of the most popular beverages all over the world which is prepared from the leaves of a shrub camellia sinensis. eastern black sea region of turkey which account for around 100% of all tea production in turkey was among the areas contaminated by chernobyl accident. materials and methods: a comprehensive study was planned and carried out to determine the level of gross α a...

Analyzing the synovial fluid is one of the common methods to diagnose the articular problems to detect the stage and express the prognosis. Such gross, cytological, and biochemical analysis of synovial fluids can aid in the diagnosis of various joint diseases. Objectives: Normal values for synovial fluid in the camels have been described previously; however, there are no reports regarding conce...

Thermodynamic characterization of the activation domain of human procarboxypeptidase A2, ADA2h, and its helix-engineered mutants was carried out by differential scanning calorimetry. The mutants were engineered by changing residues in the exposed face of the two alpha helices in order to increase their stability. At neutral and alkaline pH the three mutants, alpha-helix 1 (M1), alpha-helix 2 (M...

As a result of advancing globalization and economic activities that go beyond national borders, gross domestic product (GDP) and gross national product (GNP) are becoming dissociated. The two are the same to the extent that they measure (gross) added value generated during a specific period (e.g., one year). A difference between them is, generally speaking, the former focuses on whether economi...

Pathogenic staphylococci secrete a number of exotoxins, including alpha-toxin. alpha-Toxin induces lysis of erythrocytes and liposomes when its 3S protein monomers associate with the lipid bilayer and form a hexomeric transmembrane channel 3 nm in diameter. We have used alpha-toxin to render rat hepatocytes 93-100% permeable to trypan blue with a lactate dehydrogenase leakage less than or equal...

Fabry disease is an X-linked metabolic disorder caused by a deficiency of alpha-galactosidase A (alpha-Gal A). The enzyme defect leads to the systemic accumulation of glycosphingolipids with alpha-galactosyl moieties consisting predominantly of globotriaosylceramide (Gb3). In patients with this disorder, glycolipid deposition in endothelial cells leads to renal failure and cardiac and cerebrova...