• Bentonite fining is widely used to increase the protein stability of a wine. Some authors have proposed treatment of the juice itself, rather than the wine, to enhance fermentation performance and flavor, and increase stability. Some authors have reported that this practice yields stable wines not requiring further fining, whereas others have found no increase in stability when treating the j...

Drosophila models of tauopathies have been developed by transgenically overexpressing the disease-associated forms of tau. In this paper we report for the first time that a recently developed Grape-Seed Polyphenolic Extract (GSPE) improves the eye phenotype of a Drosophila eye model of R406W tau. GSPE-mediated improvements in this distinct in vivo neurodegeneration model for protein misfolding/...

Revalorization of the winery industry residue, grape seed is studied for the production of an oil and defatted meal with nutraceutical properties. Conventional grape seed oil extraction process is carried out by pressing at high temperature affecting the product quality. Oil extraction by cold pressing improves product quality, but it gives a low oil yield. Oil extracted is increased at the pre...

BACKGROUNDS AND OBJECTIVE Several clinical trials have shown that grape seed extract can reduce blood pressure, but the results are often irreproducible. We therefore sought to systematically evaluate the impact of grape seed extract treatment on the changes of systolic/diastolic blood pressure (SBP/DBP) by meta-analyzing available randomized controlled trials. METHODS Trial selection and dat...

introduction: excessive physical exercise overproduces reactive oxygen species. even if elite sportsmen increase their antioxidant status by regular physical training, this improvement is not sufficient to limit free radical production during the competition period which can be detrimental to the body. this study evaluates the effect of grape seed supplementation along with aerobic exercise on ...

The phytochemicals present in the grapes are responsible for nutraceutical and health benfits due to their antioxidant properties. These phytochemicals, however, vary greatly among different cultivars. In this study, we evaluated the antioxidant potential and protective role of four different Indian grape (Vitis vinifera) cultivars extracts, namely Flame seedless (Black grapes), Kishmish chorni...

Background: Infertility is a problem that now affects many couples that are causing the disintegration of many families and as a psychological crisis, a lot of stress on couples has been entered. Cyclosporine (CsA), a cyclic undecapeptideof fungal origin, is a powerful immunosuppressive agent that has markedly improved graft survival rates in organ transplantation. The drug has adverse side eff...