INTRODUCTION Patients on dialysis for end-stage renal failure are subjected to cardiac surgery with increasing frequency. End-stage renal failure is known to be an important risk factor for complications of cardiac operations performed with cardiopulmonary bypass. The aim of this study was to determine the impact of preoperative clinical status and operative variables on perioperative morbidity...

BACKGROUND The use of the bilateral internal mammary arteries has been reserved mainly for younger and low risk patients. AIM To assess the safety and efficacy of BIMA grafting in older patients (> or = 70 years). METHODS We reviewed the records of all consecutive patients > or = 70 years old who underwent coronary artery bypass surgery with a BIMA graft in our institute over a 2 year perio...

OBJECTIVE Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory response. This is mainly attributed to cytokine release caused by CPB and global myocardial ischemia. Coronary artery bypass grafting without cardiopulmonary bypass (off-pump CABG, OPCAB) is now accepted as a less invasive technique than conventional CABG. This study was...

OBJECTIVE To test the hypothesis that including preoperative electrocardiogram (ECG) characteristics with clinical variables significantly improves the new-onset postoperative atrial fibrillation prediction model. DESIGN Retrospective analysis. SETTING Single-center university hospital. PARTICIPANTS Five hundred twenty-six patients, ≥ 18 years of age, who underwent coronary artery bypass ...

Bilateral anterior ischaemic optic neuropathy occurred in two patients undergoing cardiopulmonary bypass grafting. The causes may have been vasoconstriction of the posterior ciliary arteries by increased circulating angiotensin and diminished ciliary blood flow in the setting of systemic hypotension and elevated intraocular pressure.

BACKGROUND Elevated levels of serum S100B after coronary artery bypass grafting may arise from extracerebral contamination. Serum S100B content was analyzed in several tissues, and the two dimers S100A1-B and S100BB were analyzed separately in blood. METHODS Serum, shed blood, marrow, fat, and muscle were studied in patients undergoing coronary artery bypass grafting with cardiopulmonary bypa...

BACKGROUND Surgeons have adopted off-pump coronary artery bypass grafting (OPCAB) in an effort to reduce the morbidity of surgical revascularization. However, long-term outcome of OPCAB compared with conventional coronary artery bypass grafting (CABG) remains poorly defined. METHODS AND RESULTS Using logistic regression analysis and proportional hazards modeling, short-term and long-term outc...

1. Alpert JS, Thygesen K, Antman E, Bassand JP. Myocardial infarction redefined—A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J Am Coll Cardiol 2000;36:959–69. 2. Januzzi JL, Lewandrowski K, MacGillivray TE, et al. A comparison of cardiac troponin T and creatine kinase-MB for patient evalu...

The development of cardiopulmonary bypass (CPB) and open heart surgery in the 1950s has benefited millions of people around the world over the last half century. However, it has been recognized since the beginning that there are detrimental effects to CPB. In an effort to minimize the effects of CPB, a miniaturized CPB (M-CPB) closed circuit system also known as closed circuit extracorporeal ci...

BACKGROUND The present study sought to assess the renal and liver protective effect of N-acetylcysteine through NH3 and urea metabolism in patients with chronic obstructive pulmonary disease who were scheduled for coronary artery bypass grafting surgery. MATERIAL AND METHODS Patients with chronic obstructive pulmonary disease (COPD) who were scheduled for coronary artery bypass grafting were di...