We describe a multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Denmark, 2017. Whole genome sequencing of the strain GK124 identified MSLT ST1903, NG-MAST ST1614 and all relevant resistance determinants including similar penA resistance mutations previously described in ceftriaxone-resistant gonococc...

The cutaneous eruptions which follow on gonococcal infection were first mentioned by Pedoux in 1872, and may be divided into five main groups: (1) Gonococcal Ulcers; (2) Erethema; (3) Urticaria; (4) Haemorrhage and Bullous Dermatitis; (5) Hyperkeratosis. With the exception of the first group all are toxic manifestations, and occur only in very severe cases of infection, and often with an associ...

We describe two cases of spontaneous rupture of the membranes, followed by premature labour at 32 and 34 weeks' gestation, in association with gonococcal infection.

One hundred prostitutes were interviewed about the prophylactic measures they took against infection. The use of contraceptive diaphragms and clandestine antibiotics correlated significantly with fewer gonococcal infections.

Iron is limiting in the human host, and bacterial pathogens respond to this environment by regulating gene expression through the ferric uptake regulator protein (Fur). In vitro studies have demonstrated that Neisseria gonorrhoeae controls the expression of several critical genes through an iron- and Fur-mediated mechanism. While most in vitro experiments are designed to determine the response ...

Growth of Neisseria gonorrhoeae from clinical specimens has been enhanced by the use of selective media that inhibit the simultaneous growth of other microorganisms. One explanation for this enhancement could be that certain other bacteria inhibit gonococcal growth. This hypothesis was examined by testing 167 bacterial isolates for in vitro gonococcal inhibition; 34.1% of the isolates failed to...

Background: Overall, there are over 30 different sexually transmitted infections with Neisseria gonorrhoeae being the third most frequent a reported 78 million cases per year. Gonococcal infection causes genital inflammation, which can be risk factor for others infections, particularly human immunodeficiency virus. Gonorrhea is treatable disease, but recently an increase in antibiotic resistanc...