Starting from the glucose-derived δ-lactone and the functionalized aryl bromide, the first total synthesis of naturally occurring paecilomycin B was achieved via functionalized aryl-β-C-glycoside synthesis using 2,4,6-triisopropylphenyllithium under Barbier-type reaction conditions and ring-closing metathesis as the key steps.

The family of ribosome-inactivating proteins (RIPs) groups all enzymes (EC.3.2.2.22) with a so-called RIP domain which comprises N-glycosidase activity and enables these proteins to catalytically inactivate ribosomes.[...].

For many decades, the area of alternative medicine has attracted considerable attention from researchers worldwide. Interestingly, evidence abounds that affirms efficacy in various healthcare domain. Moreso, plants properties have been well explored relating to its medicinal compositions. The purpose present study was analyze antimicrobial and bioactive contents M. Myristica seed. samples were ...