An extracellular coating was discovered by Bennet in 1963 on the luminal surface of endothelia and termed “glycocalyx”. Apparent thickness of the glycocalyx is ~ 0,5 μm. The glycocalyx consists of: proteoglycans, glycosaminoglycans (GAGs) and oligosaccharide chains of glycoproteins (some containing sialic acid residues). The amount of glycocalyx sulfate proteoglycan (SPG)-molecules vary between...

Introduction: Alteration of terminal sugars of Glycoconjugates is one of the important aspects of neoplasia. The aim of the present study was to identify GalNac and GlcNac containing glycoconjugates in different grades of neoplastic cells in adenocarcinoma of colon.  Methods: Histological sections prepared from paraffin blocks belong to 30 patient of colon adenocarcinoma obtained from Khatam...

Glycan based interactions between host and pathogen are critical in many bacterial and viral diseases. Glycan interactions range from initial receptor based adherence to protecting the infective agent from the host's immune response through molecular mimicry. Campylobacter jejuni is an ideal model for studying the role of glycans in host-pathogen interactions, as well as the role of bacterial s...

s of Communications 567th Meeting of the Biochemical Society University of Durham 6 and 7 January 1977 SECRETIONAL ASPECTS OF GLYCOCONJUGATES: a Colloquium organized by P. W. Kent (Durham) Metabolism of Proteoglycans and Glycosaminoglycans in Cultivated Fibroblasts