نتایج جستجو برای: glutathione peroxidase gshpx

تعداد نتایج: 63181  

Journal: :The American journal of Chinese medicine 2006
Jyh-Sheng You Hui-Feng Huang Ying-Ling Chang Ying-Shiung Lee

The traditional Chinese medicine prescription "sheng-mai-san (SMS)" has been used for treating patients with coronary heart disease for a long time and was found to have antioxidative effects. Here, we applied adriamycin (doxorubicin, ADR), a highly effective anticancer agent, as an inducer to establish the animal model of dose-related cardiomyopathy due to inhibition of nucleic acid as well as...

Journal: :Journal of lipid research 1996
Y Bao G Williamson

Two enzymatic mechanisms have been proposed for the metabolism of hydroperoxy-phospholipids: i) the combined action of phospholipase A2 and glutathione peroxidase, and/or ii) direct enzymatic reduction. The latter reaction may be catalyzed by selenium-dependent phospholipid hydroperoxide glutathione peroxidase and/or by glutathione S-transferase alpha. To study the pathway of this reaction, we ...

Journal: :The Journal of biological chemistry 1979
J W Forstrom A L Tappel

By isolation of a mixed disulfide product of glutathione and cysteine, glutathione peroxidase was shown to be highly specific for only one donor substrate. Using the coupled assay of NADPH and yeast glutatione reductase, which is highly specific for flutathione disulfide, it was shown that the apparent inhibition of glutathione peroxidase by mercaptoethanol can be described kinetically and that...

Journal: :Zeitschrift fur klinische Chemie und klinische Biochemie 1974
W A Günzler H Kremers L Flohé

An optimized coupled test system for glutathione peroxidase in red blood cells is presented. In the improved assay, tert. butyl hydroperoxide was employed as an acceptor substrate at twenty times Km(app) concentration. By aid of a batching procedure for instant separation of hemoglobin from glutathione peroxidase, it could be proved that cyanmethemoglobin in the modified procedure does not affe...

Journal: :Mesopotamia Journal of Agriculture 2023

Silicone and Glutathione application are including systemic acquired resistance or induced against plant diseases against. It is a successful means to control rot disease it leads fundamental effects on the physiology of host, as use in agent hostile Fusarium solani causal Broad bean root .The results this study appeared that have make less tot incidence severity plants increase resistance-Link...

Journal: :Clinica chimica acta; international journal of clinical chemistry 2004
Durdi Qujeq Hamid Reza Aliakbarpour Khodaberdi Kalavi

BACKGROUND This investigation describes the relationship between glutathione peroxidase activities, an antioxidant enzyme, and the oxidative status in diabetic rat blood. METHODS Malondialdehyde level and glutathione peroxidase activity were measured by spectrophotometric techniques. RESULTS AND CONCLUSIONS Malondialdehyde content in the diabetic rats group was increased compared to that in...

2009
Toshio Kaneko Yamaguchi Toshio Kaneko

Toshio Kaneko, MD, Third Department of Internal Medicine, Yamaguchi University School of Medicine, Koguchi, Ube Yamaguchi 755 (Japan) Oxidative damage of red cell membrane is known to be accelerated in sickle cell disease. However, the exact mechanism of this acceleration is unclear. We have read with interest the recent article entitled ‘Selenium and Glutathione Peroxidase Levels in Sickle Cel...

Journal: :iranian journal of pharmaceutical research 0
seyyed ali mard physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran mojib azad physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran akram ahangarpour physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran

the present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (i/r) injury in rats.forty male rats were randomly divided into sham, control (i/r injury) and three crocin-pretreated groups. to induce i/r lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 3 h. pretreated-rats rec...

Journal: :modares journal of medical sciences: pathobiology 2012
parvin farzanegi sadegh saberi ali fakharian mohammad javad rasaee valiollah dabidi roshan

objective: environmental pollution is of major concern today and lead is considered to be one of the most important environmental pollutants. long-term contact with lead causes harmful effects to humans. this study seeks to determine the effects of curcuma longa (turmeric extract) consumption and exercise training on glutathione peroxidase and protein carbonyl in kidney and spleen tissues from ...

Journal: :middle east journal of digestive diseases 0
shirin moossavi sima besharat maryam sharafkhah alireza ghanbari amrollah sharifi parisa rezanejad

background oxidative stress plays a major pathogenic role in liver injury following chronic hepatitis b. glutathione peroxidase (gpx) has a central role in regulating the oxidative state. hepatitis b virus (hbv) results in down-regulation of gpx. on the other hand, iron homeostasis is disrupted in hbv infected patients. therefore, the objective of this study was to assess the interplay of gpx a...

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