This study was designed to explore the protective effects of Abrus precatorius L. (Leguminosae) (AP) in HepG2 cells and N-nitrosodiethylamine (NDEA) induced hepatocellular carcinoma in Swiss albino rats. The effects of aqueous/ethanolic (50%) extract of AP on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in NDEA ...

Administration of simvastatin (80 mg/kg, po. evening dose) and gemfibrozil (600 mg/kg, po twice) for 30 days produced significant decrease in the level of reduced glutathione, superoxide dismutase, catalase and increase in the level of lipid peroxidation and various serum parameters (creatine phosphokinase, lactate dehydrogenase, serum glutamate oxaloacetate transaminase, creatinine, urea and b...

Present study was carried out to investigate different extracts of Bauhinia purpurea (B.P) for its hepatoprotective activity against CCl4 induced hepatotoxicity. The different parts of Bauhinia purpurea were collected authenticated and were subjected to extraction using solvent alcohol. Healthy wistar albino rats (150-200g) of male sex were used for the in-vivo investigations. Liver damage was ...

Wherever the point has been examined (e.g. References l-6), pyridoxal phosphate enzymes have been found to require free sulfhydryl groups for activity. The functional role played by these groups, however, has not been clear. In glutamate-oxaloacetate transaminase, which has been studied most extensively, no spectrophotometric or enzymatic evidence for their participation in coenzyme binding was...

Leaf extracts of 27 `Yuzu' and related acid citrus cultivars were analyzed using polyacrylamide gel electrophoresis for isozyme variation of glutamate oxaloacetate transaminase (GOT) and shikimate dehydrogenase (SDH). SDH yielded 12 different isozyme phenotypes and six cultivars were discriminated by this enzyme alone. GOT produced 10 different isozyme phenotypes and four cultivars were separat...