objective: this study was planned to investigate whethercoriandrum sativum (c. sativum) is capable of protecting neurons against glucose/serum deprivation (gsd)-induced cytotoxicity. material and methods: the pc12 cells were cultivated for 24 h in standard media (high-glucose dmem containing fetal bovine serum) or for 6 h in gsd condition (glucose-free dmem, without serum) in the absence or pre...

background: cornus mas l, an olive-shaped red-colored single-seeded fruit, is used in traditional medicine in different parts of europe and asia. objectives: in the present study, 40 male wistar rats were randomly divided into five groups, and the effects of 21 days of intraperitoneally (ip) administration of 50, 200 and 400 mg/kg body weight of c. mas hydro-methanolic extract on the rats hemat...

background: use of glucosamine as an alternative treatment for osteoarthritis is becoming more frequent, including in those who have diabetes at the same time. the results from in vitro and animal studies propose that glucosamine may inversely affect glucose metabolism. however, the recommended dose of oral glucosamine in healthy people or diabetics did not have such effects consistently. the a...

background : diabetes mellitus is a chronic disease with a worldwide prevalence and its complications can be prevented with close monitoring of blood glucose. quality of blood glucose monitoring utilizing glucometers in iranian hospitalized patients has not been well published in the literature. we evaluated the accuracy and consistency of the results of two devices compared with the standard l...

advanced glycation end-products (ages) are formed by non-enzymatic reaction between reducing sugar and protein. ages play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the alzheimer’s disease. therefore compounds that prevent the glycation reaction are purported to have therapeutic effect on patients with diabetes and...

this study was planned to investigate the effects of supplementation of cinnamon on fasting blood glucose levels and lipid profiles among type2 diabetic patients. 60 subjects with type 2 diabetes from both sexes (30 males and 30 females) were allocated to the intervention and control groups (30 individuals per group). t he doses of 1.5 g of cinnamon were equally administered orally in the form ...

background: the relationship between lichen planus (lp) and diabetes was studied previously, but the re-sults were in conflict. the aim of this study was to find the prevalence of diabetes mellitus (dm) in patients with lp among iranian patients. methods: in this study, 80 patients with lp were enrolled. they referred to dermatology clinic of our hospital during one year. a self-designed checkl...

Impaired glucose tolerance has several adverse effects on growing fetus. In this study we evaluated the effect of excessive weight gain during pregnancy on the risk of glucose intolerance in pregnant women. A case-control study was conducted through which the glucose tolerance status after 100 gram oral glucose intake was compared between 60 pregnant women with maximum 10 weeks of gestation and...

results coincubation of islets with vitamin d (10 nm) and 11.1 mm glucose increased islet insulin release (37.27 ± 3.75 vs. 24.64 ± 2.83 ng/islet/24 hours; p < 0.05), while vitamin d (1 and 10 nm) decreased insulin release in the presence of 16.7 mm glucose (21.14 ± 3.58 and 18.65 ± 3.84 vs. 37.71 ± 4.63 ng/ islet/24 hours; p < 0.05). islets preincubation with vitamin d (1 and 10 nm) increased ...

the effect of blood glucose level changes induced by 24h food deprivation and intraperitoneal (ip) injection of insulin (2iu/kg) and glucose (2gr/kg) was investigated on the pain induced by intraplantar (ipl) injection of formalin (20ml , 5%) in mice. blood glucose level changes were determined by blood sampling from the apex of the tail of mice. ip injection of insulin and 24h food deprivation...