نتایج جستجو برای: glucosamine

تعداد نتایج: 5089  

2009
Luyun Zou Shaolong Yang Voraratt Champattanachai Shunhua Hu Irshad H. Chaudry Richard B. Marchase John C. Chatham

Zou L, Yang S, Champattanachai V, Hu S, Chaudry IH, Marchase RB, Chatham JC. Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NFB signaling. Am J Physiol Heart Circ Physiol 296: H515–H523, 2009. First published December 19, 2008; doi:10.1152/ajpheart.01025.2008.—We have previously demonstrated that in a rat model of trauma...

2015
Sandi L. Navarro Emily White Elizabeth D. Kantor Yuzheng Zhang Junghyun Rho Xiaoling Song Ginger L. Milne Paul D. Lampe Johanna W. Lampe

BACKGROUND Glucosamine and chondroitin are popular non-vitamin dietary supplements used for osteoarthritis. Long-term use is associated with lower incidence of colorectal and lung cancers and with lower mortality; however, the mechanism underlying these observations is unknown. In vitro and animal studies show that glucosamine and chondroitin inhibit NF-kB, a central mediator of inflammation, b...

Journal: :The New England journal of medicine 2006
Daniel O Clegg Domenic J Reda Crystal L Harris Marguerite A Klein James R O'Dell Michele M Hooper John D Bradley Clifton O Bingham Michael H Weisman Christopher G Jackson Nancy E Lane John J Cush Larry W Moreland H Ralph Schumacher Chester V Oddis Frederick Wolfe Jerry A Molitor David E Yocum Thomas J Schnitzer Daniel E Furst Allen D Sawitzke Helen Shi Kenneth D Brandt Roland W Moskowitz H James Williams

BACKGROUND Glucosamine and chondroitin sulfate are used to treat osteoarthritis. The multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis. METHODS We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of g...

Journal: :Israel Journal of Chemistry 2021

In this account, we describe the application of a series multidentate BINOL-based phosphoric acids for fluorescence-based chemosensing amino sugars. To end, developed novel synthetic protocol three isomerically pure acid monoesters type ArOP(O)(OH)2. These were investigated with respect to their binding towards sugars (glucosamine, galactosamine and mannosamine) in comparison previously reporte...

Journal: :iranian chemical communication 2013
omid louie abdolhossein massoudi soodabeh ramezani

the amphiphilic graft copolymer using chitosan (cs) as hydrophilic segment and poly (l-lactic acid) (plla) as hydrophobic segment, was prepared through a protection-graft-de protection route. chitosan is a polysaccharide comprising of copolymers of glucosamine and n-acetyl glucosamine. chitosan is the deacetylated derivative of chitin, which is one of the most abundant natural polysaccharides c...

Journal: :The Journal of biological chemistry 1966
C J Bates W R Adams R E Handschumacher

Rats fed a purified diet containing 1% erotic acid for 2 days accumulate large amounts of uridine diphospho-Nacetylhexosamine in the liver. This accumulation is not the result of a block in utilization of uridine diphospho-Nacetylhexosamine, but probably results from increased synthesis de novo. These rats appear to suffer from a defect in the feedback control of L-glutamine-D-fructose 6-phosph...

2012
Tamil Selvan Kingston Rajiah M. Sundara-Moorthi Nainar Elizabeth M. Mathew

BACKGROUND Glucosamine may be effective in treating and possibly slowing the progression of Osteoarthritis (OA). It is believed Glucosamine supplements may help to stop cartilage breakdown, build cartilage and decrease swelling. OBJECTIVE The objective of this study was glucosamine sulfate versus combination of glucosamine sulfate and Non-Steroidal anti-inflammatory drugs (NSAID) in mild to m...

Journal: :Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 2013
Akın Uğraş Elif Güzel Petek Korkusuz Ibrahim Kaya Fatih Dikici Emrah Demirbaş Ercan Çetinus

BACKGROUND The aim of this study is to determine whether glucosamine-sulfate has any effects on bone-healing. METHODS A unilateral fracture was created in the tibia of sixty-one female rats. Rats were given no drug or 230 mg/kg glucosamine-sulfate daily. Fractures were analyzed during the first, second and fourth weeks after creation of fracture. Quantitative measurement for new bone formatio...

2013
Eliška VÁCLAVÍKOVÁ František KVASNIČKA

Václavíková E., Kvasnička F. (2013): Isotachophoretic determination of glucosamine and chondroitin sulphate in dietary supplements. Czech J. Food Sci., 31: 55–65. Glucosamine and chondroitin sulfate, components of normal cartilage, are used as ingredients in dietary supplements intended to treat osteoarthritis and/or to support joint health. Of concern is the documented lack of quality in many ...

Journal: :Applied and environmental microbiology 2014
Zachary D Moye Robert A Burne Lin Zeng

Glucosamine and N-acetylglucosamine are among the most abundant sugars on the planet, and their introduction into the oral cavity via the diet and host secretions, and through bacterial biosynthesis, provides oral biofilm bacteria with a source of carbon, nitrogen, and energy. In this study, we demonstrated that the dental caries pathogen Streptococcus mutans possesses an inducible system for t...

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