نتایج جستجو برای: gleason

تعداد نتایج: 4455  

Journal: :Journal of the National Cancer Institute 2005
Peter C Albertsen James A Hanley George H Barrows David F Penson Pam D H Kowalczyk M Melinda Sanders Judith Fine

BACKGROUND Information on tumor stage and grade are used to assess cancer prognosis and to produce standardized comparisons of end results over time. Changes in the interpretation of classification schemes can alter the apparent distribution of cancer stage or grade in the absence of a true biologic change. Since the introduction of prostate-specific antigen testing, the reported incidence of l...

2015
Yasushi Nakai Nobumichi Tanaka Keiji Shimada Noboru Konishi Makito Miyake Satoshi Anai Kiyohide Fujimoto

BACKGROUNDS Urologists use biopsy Gleason scores for patient counseling, prognosis prediction, and decision making. The accuracy of Gleason grading is very important. However, the variability of Gleason grading between general pathologists cannot be overlooked. Here we evaluate the discrepancy in the Gleason grading between 2 urologic pathologists and general pathologists as well as improvement...

2015
R. M. PLEȘEA M. S. ȘERBĂNESCU D. O. ALEXANDRU V. CIOVICĂ A. STOICULESCU O. T. POP CRISTIANA SIMIONESCU I. E. PLEȘEA

Purpose: The study aims to assess the correlation between stromal fibrillary component (SFC) and vascular density (VD) in Gleason architectural patterns of prostate carcinoma. Materials and Methods: 680 digital images of prostate adenocarcinoma labeled following both Gleason and Srigley systems were acquired with X20 objective from serial sections, one stained using Gömöri technique for SFC and...

Journal: :Sao Paulo medical journal = Revista paulista de medicina 2008
José Cury Rafael Ferreira Coelho Miguel Srougi

CONTEXT AND OBJECTIVE Accurate determination of the Gleason score in prostate core biopsy specimens is crucial in selecting the type of prostate cancer treatment, especially for patients with well-differentiated tumors (Gleason score 2 to 4). For such patients, an inaccurate biopsy score may result in a therapeutic intervention that is too conservative. We evaluate the role of Gleason score 2-4...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2017
Yu Yin Qingfu Zhang Hong Zhang Yiping He Jiaoti Huang

A new 30-gene signature has been described that separates prostate cancers of Gleason score ≤6 from those of Gleason score ≥8. It provides independent prognostic information for prostate cancers of intermediate risk (Gleason score of 7), which has the potential to stratify these patients into different risk groups. Clin Cancer Res; 23(1); 6-8. ©2016 AACRSee related article by Sinnott et al., p....

ژورنال: Hormozgan Medical Journal 2013
Heidari, M. , Mousavi, A. , Zare, S. ,

Introduction: Prostatic adenocarcinoma is the most common malignancy of internal system and after lung cancer is the second cause of death in male. Genetic base of many neoplasms is related to suppressor tumor gene such as P53. Therefore, we aimed in this study, to assess the intensity of prostatic adenocarcinoma tissue staining with P53 staining method and its relationship with Gleason grade. ...

Journal: :Proceedings of the American Mathematical Society 2010

Journal: :European urology 2006
Felix K-H Chun Thomas Steuber Andreas Erbersdobler Eike Currlin Jochen Walz Thorsten Schlomm Alexander Haese Hans Heinzer Michael McCormack Hartwig Huland Markus Graefen Pierre I Karakiewicz

OBJECTIVE Previous reports indicate that as many as 43% of men with low grade PCa at biopsy will be diagnosed with high-grade PCa at RP. We explored the rate of upgrading from biopsy to RP specimen in our contemporary cohort, and developed a model capable of predicting the probability of biopsy Gleason sum upgrading. MATERIALS AND METHODS The study cohort consisted of 2982 men treated with RP...

2016
Sheila F. Faraj Stephania M. Bezerra Kasra Yousefi Helen Fedor Stephanie Glavaris Misop Han Alan W. Partin Elizabeth Humphreys Jeffrey Tosoian Michael H. Johnson Elai Davicioni Bruce J. Trock Edward M. Schaeffer Ashley E. Ross George J. Netto Xin Gao

In 2005, the International Society of Urological Pathology (ISUP) introduced several modifications to the original Gleason system that were intended to enhance the prognostic power of Gleason score (GS). The objective of this study was to clinically validate the 2005 ISUP Gleason grading system for its ability to detect metastasis. We queried our institutional RP database for men with NCCN clin...

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