نتایج جستجو برای: girk2
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This month's installment of Generally Physiological concerns G protein–gated inward rectifier K + (GIRK) channel activation and role in the regulation of heart rate, intermembrane transfer of vitamin E, and identification of a ligand-inducible vertebrate fluorescent protein. A new twist in GIRK activation Neurotransmitters that signal through G protein–coupled receptors (GPCRs) can activate GIR...
To investigate possible effects of adrenergic stimulation on G protein-activated inwardly rectifying K(+) channels (GIRK), acetylcholine (ACh)-evoked K(+) current, I(KACh), was recorded from adult rat atrial cardiomyocytes using the whole cell patch clamp method and a fast perfusion system. The rise time of I(KACh ) was 0. 4 +/- 0.1 s. When isoproterenol (Iso) was applied simultaneously with AC...
Mesencephalic-diencephalic dopaminergic (mdDA) neurons control motor, sensorimotor and motivated behaviour and their degeneration or abnormal functioning is associated with important pathologies, such as Parkinsons disease and psychiatric disorders. Despite great efforts, the molecular basis and the genetic factors differentially controlling identity, survival and vulnerability to neurodegenera...
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