Idiopathic gingival enlargement is a type of gingival fibromatosis characterized by progressive overgrowth of the gingival tissues.This case report presented the clinical features of a typical idiopathic gingival enlargement which was treated with external bevel gingivactomy. The patient presented with generalized diffuse gingival enlargement involving the maxillary and mandibular arches extend...

Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant procedures. Azithromycin has been used successfully for managing gingival overgrowth in human transplant patients when cyclosporine administration canno...

Gingival hyperplasia can occur during use of drugs such as diphenylhydantoin, cyclosporine and nifedipine. We report, three cases of gingival hyperplasia induced by amlodipine, a second generation calcium channel blocker. Exact cause of induction of thehyperplasia is not known. Individual variation in metabolism of the drug may be a factor.

OBJECTIVE To evaluate the effect of periodontal treatment on gingival overgrowth in a group of renal transplant patients. SUBJECTS AND METHODS Twenty-five renal transplant recipients receiving immunosuppressive therapy with cyclosporine A (CsA) were randomly assigned to 2 groups. Group 1 (n = 15) included patients who had been specifically referred to a dental clinic to prevent gingival overg...

Introduction: Gingival enlargement is the term now used to describe medication-related gingival overgrowth or gingival hyperplasia, a common reactionary phenomenon that occurs with the use of several types of therapeutic agents, including antiepileptic drugs. This disorder has been recognized since 1939, shortly after the introduction of phenytoin. Methods: Review of literature concerning etiol...

pregnancy tumor is a benign, hyperplastic lesion of the gingiva, considered to be reactive or traumatic rather than neoplastic in nature. the term pyogenic granuloma is a misnomer as it is not filled with pus or granulomatous tissue histologically. it is multi factorial in nature, which shows an exaggerated response to stimuli such as low grade or chronic irritation, trauma or hormonal variatio...

Gingival enlargement or gingival overgrowth is the abnormal growth of periodontal tissues. Drug induced gingival enlargement is one of the most common cause of enlarged gingiva. Drugs associated with gingival enlargement are divided in to three major groups namely anticonvulsants, immunosuppressant and calcium channel blockers [1]. Among the anticonvulsants, phenytoin is most commonly associate...

Background: The mechanism concerning gingival overgrowth as a side effect of phenytoin, a therapeutic drug for epilepsy has been still unclear. As one of mechanisms, by measuring the intracellular calcium concentration ([Ca]i) of the gingival fibroblasts, it has been advocated that there is relationship between gingival overgrowth and phenytoin-induced alterations in the [Ca]i in gingival fibro...

BACKGROUND Inflammatory gingival enlargement is a common observation in routine dental practice. Drugs like nifedipine, used for hypertension and Porphyromonas gingivalis infection-induced gingival enlargement is of a major concern. The current study aims to identify the inflammatory response of the gingival enlargement by measuring the major inflammatory markers fibrinogen and C-reactive prote...