the purpose of the present randomized clinical trial study was to compare the effectiveness of bovine porous bone mineral (bpbm) with and without plasma rich in growth factors (prgf) in the treatment of mandibular class ii furcation defects.in seven patients, nine pairs of symmetric buccal or lingual mandibular class ii furcation defects were treated. in each patient, one defect received bpbm (...

the alteration of cytokine balance is stated to exert greater influence on gingival overgrowth compared to the direct effect of the drug on the regulation of extracellular matrix metabolism. the current study evaluated the effect of phenytoin on the regulation of collagen, lysyl oxidase and elastin in gingival fibroblasts.normal human gingival fibroblasts (hgfs) were obtained from 4 healthy chi...

This case report describes a unique creeping attachment that developed mesiobucally on a deep, wide recession (3 mm) and extended along the remaining buccal recession (2 mm) of a maxillary first molar with a full-crown gold restoration subsequent to autogenous gingival grafting. Complete coverage of the root by this degree of creeping attachment on a restored multirooted tooth has not previousl...

statement of the problem: recently allogenic mesenchymal stem cells are proposed to have multipotential progenitor cell capabilities to differentiate into cementoblasts, osteoblasts, and periodontal ligament fibroblasts. purpose: the aim of the present study was to compare the efficacy of human umbilical stem cells cultured on polylactic acid (pla), polyglycolic acid (pga) membrane with pla/pga...

Common risk factors of periodontitis and cardiovascular diseases fuel the debate on interrelationships between them. The aim is to prove whether statins may influence periodontal parameters by affecting either of these factors. Out of the 4,290 subjects of SHIP (Study of Health in Pomerania), we included subjects aged >30 years (219 with statins, 2937 without) and excluded edentulous. We determ...

In 28 adult severe periodontitis patients who did not respond to conventional periodontal therapy, full mouth clinical parameters including probing pocket depth, relative attachment level, bleeding on probing and suppuration after probing, visible plaque index and modified gingival index were recorded at the baseline and 14 months after treatment. Based on clinical and bacteriological diagnosis...

Background  Recent investigations show that both proliferation and secretion of macromolecules by cells can be regulated by low level laser therapy (LLLT). The aim of this study was to determine whether LLLT could induce a bio-stimulatory effects on human gingival fibroblasts (HGF3-PI 53). Therefore, the effect of laser irradiation on human gingival cell proliferation and collagen type I gene ...