Hereditary gingival fibromatosis (HGF) is a rare, benign disorder with slowly progressive enlargement of maxillary and mandibular gingiva. Herewith, we report the first case series of HGF presenting among mother and all of her 3 children. Their complaints included unaesthetic appearance due to gingival growth, malocclusion, and difficulty in mastication. Conventional gingivectomy with oral hygi...

Gingival overgrowth is, among other things, a side effect of the administration of dihydropyridine antihypertensives, generally associated with irritant factors of marginal periodontium. This case refers to a patient, female, who developed a large gingival enlargement that has a combined etiology: the systemic medication with lercanidipina and the presence of dental bridges, which are incorrect...

Steroid sex hormones have a significant effect on different organ systems. As far as gingiva are concerned, they can influence the cellular proliferation, differentiation and growth of keratinocytes and fibroblasts. Estrogen is mainly responsible for alterations in blood vessels and progesterone stimulates the production of inflammatory mediators. In addition, some micro-organisms found in the ...

Inflammatory gingival enlargement is an excessive growth of tissue due to inflammation in response plaque accumulation. Enlargement gingiva hampers the efficiency daily oral hygiene practices which turn accumulates more plaque, thus causing inflammation. Phase I therapy, consisting scaling and root planning only reduces inflammatory component enlarged tissues but fibrotic remaining thereafter t...

Introduction: Drug-induced gingival overgrowth (DIGO) remains a significant problem for the dental clinicians and the periodontologists. Patients medicated with certain drugs may be implicated in this unwanted side effect, which may interfere with esthetics, mastication or speech. Case Report: The case presented here is a 60-year-old female patient with drug induced gingival enlargement. Patien...

Background. Hereditary gingival fibromatosis is a fibrotic enlargement of the gingiva. It may exist as an isolated abnormality or as part of multisystem syndrome. This paper reports a case of 16-year-old male with generalized severe gingival overgrowth, involving the maxillary and mandibular arches and covering almost all teeth. Methods. Periodontal management of gingival enlargement included g...

Functional heterogeneity exists among fibroblasts in gingiva. There is remarkable variation in the protein synthetic activities, the proliferative capacities and the drug-response potentials of various subpopulations of such cells. These functional differences may play a role in the pathogenesis of phenytoin-induced gingival enlargement, as subpopulation mixtures are altered by conditions withi...