Objective: Although frequently regarded as a low grade malignancy, basal cell carcinoma (BCC) sometimes shows aggressive behavior. Giant BCC is defined as a lesion greater then 5 centimeter. Material and Methods: The authors described the diagnosis and treatment protocol of giant BCC, involving lumbosacral region without any local or distant metastasis. Also the authors went through a thorough...

verrucous carcinoma is a unique clinical and pathological entity which has been recognised in the recent years. it is a variant of well-differentiated squamous cell carcinoma which may occur in the larynx; other anatomic locations such as: the oral cavity, anogenital region, and skin may be involved. it accounts for 1-2% of all laryngeal cancers. the clinical, histopathological and biologic fea...

giant cell tumors (gct) are benign tumors with potential for aggressive behavior and capacity to metastasize. although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. its histogenesis remains unclear. it is characterized by a proliferation of mononuclear stromal ce...