The monoterpene fraction of the lemon-scented sweet basil (Ocimum basilicum) cv Sweet Dani consists mostly of citral (a mixture of geranial and neral), with lower levels of geraniol and nerol. These compounds are stored in the peltate glands found on the leaf epidermis. Younger leaves, which have a higher density of such glands, also have a higher content of monoterpenes than older leaves. Gera...

Background: Essential oil content and composition in medicinal and aromatic plants is highly affected by both biotic and abiotic factors. Objective: To investigate the effects of drought stress, zeolite and bio-fertilizers on morphological characteristics and essential oil constituents in Dracocephalum moldavica L. Methods: This experiment was conducted in the form of split factorial based on...

Background and Objectives: Listeria monocytogenes is an emerging foodborne pathogen which may be transmitted through meat and dairy products to humans. In this study, effects of Cuminum cyminum essential oil (CCEO) and Biarum carduchcorum water extract (BCWE) and a combination of the two compounds on growth of L. monocytogenes and physicochemical, textural and sensory properties of lambs were i...

Abstract Background The Essential oils (EOs) are important bioactive secondary metabolites of aromatic plants, such as Basil, and find extensive utilization in pharmaceutical sector therapeutic agents. A more eco-friendly industrial production EOs requires new sustainable methods to improve yield quality these compounds plants. Here, we evaluated the biostimulation effects natural organic mater...

The conversion of geranyl pyrophosphate to (-)-endo-fenchol is considered to proceed by the initial isomerization of the substrate to (-)-(3R)-linalyl pyrophosphate and the subsequent cyclization of this bound intermediate. To test this stereochemical scheme, phosphatase-free preparations of (-)-endo-fenchol cyclase from fennel (Foeniculum vulgare M.) fruit were repeatedly incubated with a samp...

Long chain cis-prenyltransferase in rat liver microsomes was studied using various allylic isoprenoid substrates. Microsomes could utilize trans-geranyl pyrophosphate, but not cis-geranyl pyrophosphate for polyprenyl pyrophosphate synthesis. Both trans, trans-farnesyl pyrophosphate and trans,cis-farnesyl pyrophosphate were used as substrates with Km values of 24 and 5 microM, respectively. tran...

Osteoporosis and low bone mass are currently estimated to be a major public health risk affecting >50% of the female population over the age of 50. Because of their bone-selective pharmacokinetics, nitrogen-containing bisphosphonates (N-BPs), currently used as clinical inhibitors of bone-resorption diseases, target osteoclast farnesyl pyrophosphate synthase (FPPS) and inhibit protein prenylatio...

Furaquinocin is a natural polyketide-isoprenoid hybrid (meroterpenoid) that exhibits antitumor activity and is produced by the Streptomyces sp. strain KO-3988. Bioinformatic analysis of furaquinocin biosynthesis has identified Fur7 as a possible prenyltransferase that attaches a geranyl group to an unidentified polyketide scaffold. Here, we report the identification of a physiological polyketid...