• duchenne muscular dystrophy o onset 3 to 5 yrs o clinical § weakness o distribution § proximal > distal § symmetric § legs & arms § most involved muscles: adductor magnus in legs § relatively spared muscles: gracilis & sartorius o course § reduced motor function by 2 to 3 years § steady decline in strength: after 6 to 11 years o gowers sign: standing up with the aid of hands pushing on knees ...

This paper summarizes answers to frequently asked questions about the iOS keychain weakness described in [HB11]. It provides further information for security evaluators on the impact of the findings.

JCB • VOLUME 168 • NUMBER 6 • 2005 850 Acyl cycles move Ras cyl groups cycle endlessly on and off Ras to confine the protein to the Golgi and plasma membrane (PM), as shown by Oliver Rocks, Alfred Wittinghofer, Philippe Bastiaens (EMBL, Heidelberg, Germany), and colleagues. These locales are the homes of two Ras isoforms, Nras and Hras, both of which are modified with the acyl group palmitate. ...

IntroductIon Until some decades ago, health care services were primarily supplied inside hospitals. The patient had to move from his or her home to the hospital, where various diagnostic and therapeutic treatments were provided. Moreover, inside the same hospital, the various tools and processes were insulated and autonomous. Patients and doctors had to move from one tool to another, often plac...

Overuse can be defined as the chronic overloading of muscles in daily life activities resulting in physical complaints such as muscle fatigue and pain. Overuse can develop in case of a reduced capacity of muscle to endure loads due to paresis (slight or partial paralysis), but also when normal muscle is chronically overloaded, for instance when a muscle has to compensate for other paretic muscl...

measures varies and may overestimate asthma control: an analysis of the goal study. J Asthma 2007;44:667–73. 27. Bereznicki BJ, Peterson GM, Jackson SL, et al. Pharmacist-initiated general practitioner referral of patients with suboptimal asthma management. Pharm World Sci 2008;30:869–75. 28. Price D, Thomas M. Breaking new ground: challenging existing asthma guidelines. BMC Pulm Med 2006;6(Sup...

The Apostle Paul can rightly be regarded as "the Theologian of Weakness." Yet Paul's theology of weakness developed in a dynamic fashion in response to the situations facing him, and his particular formulations are consistently adapted and designed to meet particular issues at hand. Nowhere is this more clearly seen than in those letters in which the apostle finds himself forced to answer the c...

We report a 51-year-old male with a history of palpitations, hepatopathy and hypercholesterolemia, who habitually ate raw goat meat, and developed general fasciculations, muscle cramps in the lower limbs, distal muscle weakness and wasting, without upper motor neuron signs or sensory abnormalities. Diagnostic workup revealed positive antibodies against Toxocara canis in the serum and cerebrospi...

Chronic pain in the Achilles tendon. Access to the published version may require subscription. PREFACE According to Greek mythology, the legendary warrior Achilles was invulnerable except for his heel. It is written in the Iliad that he died due to an arrow that pierced his Achilles tendon, thus the " Achilles' heel " came to symbolise a person's principal weakness. Nowadays, weakness of the Ac...