نتایج جستجو برای: gene expression il 1b
تعداد نتایج: 1705519 فیلتر نتایج به سال:
مقدمه: هلیکوباکتر پیلوری علت اصلی التهاب مزمن و زخم پپتیک میباشد، بیش از نیمی از مردم جهان به هلیکوباکتر مبتلا میشوند در حالیکه تنها 20 درصد افراد عوارض بالینی بیماری را نشان میدهند. اخیراً مشخص شده است که پاسخهای التهابی بخش مهمی از بیماریزایی زخم پپتیک میباشد. اینترلوکین 1b interlukine(il)- سایتوکینی است که نقش کلیدی در پاسخهای التهابی موکوس معده بازی میکند. در این مطالعه، هدف ما بررس...
Rhinovirus (RV), a ssRNA virus of the picornavirus family, is a major cause of the common cold as well as asthma and chronic obstructive pulmonary disease exacerbations. Viral dsRNA produced during replication may be recognized by the host pattern recognition receptors TLR-3, retinoic acid-inducible gene (RIG)-I, and melanoma differentiation-associated gene (MDA)-5. No study has yet identified ...
Despite the progress made in the early detection and treatment of prostate adenocarcinoma, the metastatic lesions from this tumor are incurable. We used genome-wide expression analysis of human prostate cancer cells with different metastatic behavior in animal models to reveal that bone-tropic phenotypes upregulate three genes encoding for the cytokine interleukin-1b (IL-1b), the chemokine CXCL...
Despite the progress made in the early detection and treatment of prostate adenocarcinoma, the metastatic lesions from this tumor are incurable. We used genome-wide expression analysis of human prostate cancer cells with different metastatic behavior in animal models to reveal that bone-tropic phenotypes upregulate three genes encoding for the cytokine interleukin-1b (IL-1b), the chemokine CXCL...
S chizophrenia and affective psychoses are severe and prevalent psychiatric disorders described in all cultures and populations. Whether these functional psychoses are two distinct disorders, or are closely related in aetiology, has been debated in the literature during the last century. Several studies have suggested that schizophrenia and bipolar disorder are on a continuum of liability. Psyc...
Introduction: Metabolic syndrome is a common clinical anomaly, with an increased risk of developing type 2 diabetes and cardiovascular risk factors. Increased inflammatory mediators, such as reactive protein,as well as the inflammatory cytokines can be associated with the incidence and progression of metaboli syndrome and type 2 diabetes. Materials & Methods: This study was performed on 35 m...
objective(s): interleukin-12 (il-12) as a cytokine has been proved to have a critical role in stimulating the immune system and has been used as immunotherapeutic agents in cancer gene therapy. chitosan as a polymer, with high ability of binding to nucleic acids is a good candidate for gene delivery since it is biodegradable, biocompatible and non-allergenic polysaccharide. the objective of the...
PurposeAnti-rejection immunosuppression is a persistent challenge in lung transplantation. We envisioned creating less immunogenic donor organs to obviate or reduce the need for immunosuppression. To induce expression of immunomodulatory cytokine IL-10, we aimed harness CRISPR-Cas-mediated genome editing. hypothesized that mutating regulatory region IL-10 could upregulation with practicality or...
مقدمه: هلیکوباکتر پیلوری علت اصلی التهاب مزمن و زخم پپتیک میباشد، بیش از نیمی از مردم جهان به هلیکوباکتر مبتلا میشوند در حالیکه تنها 20 درصد افراد عوارض بالینی بیماری را نشان میدهند. اخیراً مشخص شده است که پاسخهای التهابی بخش مهمی از بیماریزایی زخم پپتیک میباشد. اینترلوکین 1b interlukine(il)- سایتوکینی است که نقش کلیدی در پاسخهای التهابی موکوس معده بازی میکند. در این مطالعه، هدف ما بررس...
Background: Tegument protein pp150 of cytomegaloviruses (CMVs) plays a vital role in all stages of viral life cycle, representing the most important tegument protein candidate for HCMV treatment. However, the exact role of pp150 in immune regulation is yet to be elucidated. Objective: To examine the effects of pp150 on the maturity and function of muri...
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