Introduction In critically ill patients early enteral nutrition (EN) preserves gastrointestinal (GI) integrity and motility and should be started as early as possible. We know that several therapeutic strategies, e.g. catecholamines or analgosedation, exert adverse effects on GI motility. What we do not know is whether therapeutic hypothermia has an influence on GI motility and thereby feeding ...

background nonalcoholic fatty liver disease (nafld) is the most common cause of chronic liver disease in western world. however, nafld shows an increasing trend in china every year, which has attracted the attention of national health authorities. the previous studies have shown that nafld caused severe gastrointestinal motor disorders, but little is known about the interstitial cells of cajal ...

The importance of gastrointestinal motility and gut perception in medicine has been long recognized. Physiologically, these key functions ensure normal unperceived feeding and digestion, crucial aspects of health and wellbeing. Conversely, pathophysiological disturbances may produce digestive symptoms, which are common in the general population and may range from the simply annoying to the inca...

Functional gastrointestinal disorders (FGIDs) represent a group of chronic and recurrent symptoms in the absence any organic proven disorder [1]. There are several factors involved pathogenesis, although no single cause could be identified addressed properly, like motility disturbances, genetic implications, environmental factors, visceral sensitivity, psychologic alterations, gut-brain disturb...

BACKGROUND Gastrointestinal motility disorder has been demonstrated to be regulated by acupuncture treatment. The mechanisms underlying the effects of acupuncture stimulation of abdominal and lower limb acupoints on gastrointestinal motility have been thoroughly studied; however, the physiology underlying the effects of acupuncture on the forelimbs to mediate gastrointestinal motility requires ...

There is an increasing awareness of the role of macrophages in the regulation and maintenance of gastrointestinal function in health and disease. This work has proceeded in the context of an increased understanding of the complex phenotypic variation in macrophages throughout the body and has revealed previously un-identified roles for macrophages in diseases like gastroparesis, post-operative ...

The plant Cannabis has been known for centuries to be beneficial in a variety of gastrointestinal diseases, including emesis, diarrhea, inflammatory bowel disease and intestinal pain. delta9-tetrahydrocannabinol, the main psychotropic component of Cannabis, acts via at least two types of cannabinoid receptors, named CB1 and CB2 receptors. CB1 receptors are located primarily on central and perip...

The gastrointestinal research in domestic animals in Poland is briefly discussed in the section. The history starts over seventy years ago with the creation of the Department of Animal Physiology at the Veterinary Faculty of Warsaw University. Professor B. Gutowski, the first head of the Department, and his pupils established the School of Gastrointestinal Physiology; renowned for the achieveme...

Irritable bowel syndrome (IBS) is a spectrum of disorders characterized by abdominal discomfort and pain, associated with altered bowel habits. Though gut motility, secretion and sensation may be altered in patients with IBS, the pathophysiology of this condition remains to be fully understood. The endocannabinoid system is involved in the regulation of numerous gastrointestinal functions inclu...