Submucosal tunneling bloc biopsy for submucosal tumors growing inside the gastric wall is a safe and reliable method. However, it is difficult for an endoscopist to perform submucosal tunneling bloc biopsy and detect the demarcation line between the proper muscular layer and the capsule layer of submucosal tumors growing outside the gastric wall. A submucosal tumor in the lesser curvature of th...

Gastric adenocarcinoma is the second leading cause of death due to cancer in the world and in advanced stages the prognosis is poor with current therapies. Over-expression of HER-2/neu has been seen in several cancers such as gastric cancer and its expression is associated with poor prognosis. The aim of this study is to evaluate the over-expression of HER-2/neu in gastric biopsy samples of pat...

The aim of the study was to ascertain presence of Helicobacter pylori in gastric carcinoma as a responsible promoter of inflammatory-regenerative changes, which lead to pathological differentiation and transformation of normal epithelial cells into intestinal type and, in progression, cause epithelial dysplasia that develops into early gastric carcinoma. The paper presents prospective study tha...

Objectives. Gastric intestinal metaplasia (IM) is frequently encountered and is considered a precursor of gastric adenocarcinoma. In the Van region of Turkey, gastric adenocarcinoma incidence is high but the prevalence of gastric IM is not known. Helicobacter pylori (H. pylori) infection is a main factor leading to atrophy, IM, and cancer development in the stomach. The aim of the current study...

Gastric cancer is the third-most-common cause of cancer-related deaths in world. Fortunately, it can be detected using endoscopy equipment. Computer-aided diagnosis (CADx) systems help clinicians identify from gastric diseases more accurately. In this paper, we present a CADx system that distinguishes and classifies pre-cancerous conditions, such as polyps, ulcers, gastritis, bleeding. The uses...

IntroductIon: Gastric cancer is one of the most common causes of cancer mortality worldwide including Nepal too. According to World Health Organization (WHO) Helicobacter pylori (H. Pylori) has been shown to induce the development of adenocarcinomas. Histological confirmation of stomach cancer or the presence of H. pylori infection on tissue sample is still considered the gold standard. Methods...

The aim of this study was to compare published Helicobacter pylori primer pairs for their ability to reliably detect H. pylori in gastric biopsy specimens and salivary samples. Detection limits of the 26 PCR primer pairs previously described for detection of H. pylori DNA in clinical samples were determined. Sensitivity and specificity were determined using primers with detection limits of <100...