نتایج جستجو برای: gail model
تعداد نتایج: 2104722 فیلتر نتایج به سال:
Early phase chemoprevention trials differ from standard therapeutic clinical trials because asymptomatic, healthy people are treated with a potentially toxic intervention for a prolonged period of time. Current subject selection protocols have relied upon epidemiological methods to identify high-risk individuals. Most available data provide risk estimates for various individual risk factors, bu...
We appreciate the comments by Yamamoto et al. [1] regarding our recent article [2]. We understand the questions regarding our statistical methods with respect to the propensity matching, but in our opinion, the methods used were appropriate in addressing the question of whether video assisted thoracic surgery (VATS) lobectomy is oncologically equivalent to open lobectomy with respect to overall...
BACKGROUND Adding genotypes from seven single-nucleotide polymorphisms (SNPs), which had previously been associated with breast cancer, to the National Cancer Institute's Breast Cancer Risk Assessment Tool (BCRAT) increases the area under the receiver operating characteristic curve from 0.607 to 0.632. METHODS Criteria that are based on four clinical or public health applications were used to...
Genetic testing of seven single-nucleotide polymorphisms (7SNP) can improve estimates of risk of breast cancer relative to the Gail risk test alone, for the purpose of recommending MRI screening for women at high risk. A simulation of breast cancer and health care processes was used to conduct a virtual trial comparing the use of the 7SNP test with the Gail risk test to categorize patients by r...
INTRODUCTION Known prediction models for breast cancer can potentially by improved by the addition of mammographic density and common genetic variants identified in genome-wide associations studies known to be associated with risk of the disease. We evaluated the benefit of including mammographic density and the cumulative effect of genetic variants in breast cancer risk prediction among women ...
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