Cutaneous fungal infections remain a clinical problem. Among fungi, dermatophyte molds are the major cause of various type of Tinea. These infections are still difficult to manage and some of the antifungal agent are poorly tolerated or have been associated with emergence of resistance. The traditional methods, especially the use of medicinal plants place an imperative role to cover the basic h...

Cutaneous fungal infections remain a clinical problem. Among fungi, dermatophyte molds are the major cause of various type of Tinea. These infections are still difficult to manage and some of the antifungal agent are poorly tolerated or have been associated with emergence of resistance. The traditional methods, especially the use of medicinal plants place an imperative role to cover the basic h...

BACKGROUND Disease specific mortality is often used as outcome rather than total mortality in clinical trials. This approach assumes that the classification of cause of death is unbiased. We explored whether use of fungal infection-related mortality as outcome rather than total mortality leads to bias in trials of antifungal agents in cancer patients. METHODS As an estimate of bias we used re...

AIM To identify factors related to serious postoperative bacterial and fungal infections in the first 3 mo after living donor liver transplantation (LDLT). METHODS In the present study, the data of 207 patients from 2004 to 2011 were reviewed. The pre-, intra- and post-operative factors were statistically analyzed. All transplantations were approved by the ethics committee of West China Hospi...

Fungal plant pathogenicity is facilitated by effector proteins that are specifically expressed during infection and are responsible for suppressing plant defense mechanisms. Recent studies have elucidated the detailed molecular mechanisms of effector action throughout fungal infection. However, little is known about the trafficking and secretion of effectors in fungal hyphae during the initial ...

Seventy-two patients undergoing allogeneic transplantation were treated with voriconazole (VOR) as antifungal prophylaxis starting from day -2 of transplantation and continuing until withdrawal of immunosuppression. Patients were assessed for safety and the incidence of definite, probable, or possible fungal infection throughout transplantation was evaluated. VOR was well tolerated. Only 14% of...

Biofilms pose a serious problem for public health. Penetration of pharmacological agents within a biofilm is hampered by the morphological structure of such microbial communities. A biofilm infection therefore entails adverse outcomes both in the field of cost management and patient prognosis. The problem is further complicated if the drugs available to combat a biofilm-related fungal infection...

Mucormycosis is an opportunistic fulminant fungal infection, which mainly infects immunocompromised patients. Infection with mucormycosis can cause devastating rhino-orbital-cerebral and pulmonary infection with an extremely poor prognosis. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. We report a case of mucormycosis in an uncontrolled diabetic pati...

  Introduction : The decreased level of immunity in Human Immunodeficiency Virus (HIV) infected patients increases their vulnerability to various opportunistic fungal infections. Oral candidiasis has been found to be the most common fungal infection among HIV infected patients. The present study was conducted to evaluate the spectrum of various opportunistic fungal infections and their correlat...

The aim of this study is to calculate the burden of fungal disease in Denmark. We identified all published epidemiology papers reporting fungal infection rates in Denmark. Where no data existed, we used numbers of specific populations at risk and fungal infection frequencies in those populations to estimate national incidence or prevalence. Approximately, one in six Danes will suffer from a fun...