Fifteen compounds reported to be inhibitors of gelation or sickling were studied by standard methods. These tests included (1) the determination of the solubility of deoxyhemoglobin S or Csat, (2) evaluation of sickling in whole SS blood at various pO2s, (3) measurement of the oxygen affinity of hemoglobin and blood, and (4) examination of red cell indices and morphology. Among the 4 noncovalen...

Osteoprotegerin, a member of the tumor necrosis factor receptor superfamily, has pleiotropic effects on bone metabolism, endocrine function, and the immune system. Myocardial expression and circulating levels of osteoprotegerin are increased in heart failure. The relationship between osteoprotegerin levels in the general population and indices of left ventricular structure and function is unkno...

In 88 patients with pectus deformities radiologic chest indices and routine pulmonary function tests were measured before and 1 to 20 years after corrective surgery. A combination of anteroposterior indices at the upper and lower level of the chest were investigated to quantitate and to discriminate the different pectus deformities. The study comprised four groups: pectus excavatum, pectus cari...

Multiple regression analysis was used in order to evaluate the independent contribution and combined use of mechanocardiographic indices for assessing cardiac function in 23 patients with coronary artery disease. Three indices were derived from the quantitative displacement left apex cardiogram: the time from the onset of electrical depolarisation to the peak of the first derivative (t peak dD/...

A high prevalence of iron deficiency was found in apparently healthy Asian immigrant children in Harrow. After excluding children with overtly abnormal red cell indices, Asian and European children had identical haemoglobin values, but Asian children had much lower mean cell volume and mean corpuscular haemoglobin values and higher red blood cell values.

OBJECTIVE Many state trauma registries contain work-related information but are underutilized for occupational injury research/surveillance. We assessed three methods of identifying work-related injuries in the Washington State Trauma Registry (WTR). METHODS State-designated trauma facilities report traumatic injuries meeting specific inclusion criteria to the WTR. The WTR reports from 1998 t...

OBJECTIVES To explore injured patients' experiences of trauma care to identify areas for improvement in service delivery. DESIGN, SETTING AND PARTICIPANTS Qualitative study using in-depth, semi-structured interviews, conducted from 1 April 2011 to 31 January 2012, with 120 trauma patients registered by the Victorian State Trauma Registry and the Victorian Orthopaedic Trauma Outcomes Registry ...

Managers of the nearly 0.5 million ha of public lands in North and South Dakota, USA rely heavily on manual measurements of canopy height in autumn to ensure conservation of grassland structure for wildlife and forage for livestock. However, more comprehensive assessment of vegetation structure could be achieved for mixed-grass prairie by integrating field survey, topographic position (summit, ...

Highway work zones interrupt regular traffic flows and create safety problems. Improving safety without sacrificing the main function of highways is a challenging task that traffic engineers and researchers have to confront. In this study, the concept of using crash severity index (CSI) for work zone safety evaluation was proposed and a set of CSI models were developed through the modeling of w...

*Peripheral neutrophils were supported pretransplant by recombinant granulocyte colony stimulating factor. Post-transplant parameters were obtained at 18 months (FBC and T-cell indices, lung function) or 21 months post-HSCT (B cell and antibody indices). Post-HSCT antibody indices were measured during concomitant subcutaneous immunoglobulin supplementation. No other autoantibodies were detected...