This research was designed to study the effect of bitter almond oil on the healing of open skin wounds in rats. Thirty female adult rats were randomly divided into experimental (n=15) and control (n=15) groups. Under general anesthesia and sterile conditions, one quadrangular (surface area=22 mm) full thickness skin wound was made on the dorsum of each rat. The day of surgery was considered as ...

Graft-assisted healing is an important strategy for treating full-thickness skin wounds. This study evaluated the properties of porcine cholecyst-derived scaffold and its use for treating full-thickness skin wound in rabbit. The physical properties of cholecyst-derived scaffold were congenial for skin-graft application. Compared to a commercially available skin-graft substitute made of porcine ...

OBJECTIVE To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials. DATA SOURCES Cochrane Library, MEDLINE, EMBASE, PubMed, reference lists and databases were used to seek randomised controlled trials. Seven randomised trials involved superficial burns, partial thickness burns, moderate to severe burns that included full thickness...

BACKGROUND Burn infliction techniques are poorly described in rat models. An accurate study can only be achieved with wounds that are uniform in size and depth. We describe a simple reproducible method for creating consistent burn wounds in rats. METHODS Ten male Sprague-Dawley rats were anesthetized and dorsum shaved. A 100 g cylindrical stainless-steel rod (1 cm diameter) was heated to 100℃...

The human placenta, a complex organ, which facilitates exchange between the fetus and the mother, contains abundant extracellular matrix (ECM) components and well-preserved endogenous growth factors. In this study, we designed a new dermal substitute from human placentas for full-thickness wound healing. Highly porous, decellularized ECM sheets were fabricated from human placentas via homogeniz...

The objective of this case series was to describe and evaluate full-thickness skin grafting of equine wounds. Six adult horses were used in the study. A full-thickness graft was harvested from the pectoral region with the horse anaesthetised or standing and sedated after local anaesthetic infiltration. Grafts were attached to the cutaneous margin of the wound with staples and/or sutures if the ...

Full-thickness wounds that have rendered patients candidates for amputation may require techniques that may include a combinatorial approach above traditional standard of care. The purpose of this retrospective study was to evaluate the effectiveness of an innovative approach whereby several therapies were combined to avoid amputation. Patients with full-thickness wounds who were previously rec...