Overt stroke, clinically "silent" cerebral infarct, and neurocognitive impairment are frequent complications of sickle cell anemia (SCA). Current imaging techniques have limited sensitivity and specificity to identify children at risk for neurocognitive impairment. We prospectively evaluated 24 children with SCA with a neurologic exam, complete blood count, transcranial Doppler ultrasound (TCD)...

OBJECTIVE To assess the impact of components of the national programme for information technology (NPfIT) on measures of clinical and operational efficiency. DESIGN Quasi-experimental controlled before and after study using routinely collected patient level data. SETTING Four NHS acute hospital trusts in England. DATA SOURCES Inpatient admissions and outpatient appointments, 2000-5. INT...

The clinical significance of low serum vitamin B12 levels in elderly people is controversial. We aimed to document the prevalence of a low serum vitamin B12 (< 175 pmol/l) in patients referred to a geriatric medical unit, and to determine whether haemopoiesis is commonly affected in elderly patients with low serum vitamin B12. We studied prospectively 472 consecutive referrals to a geriatric me...

Submit Manuscript | http://medcraveonline.com Abbreviations: ALD: Alcoholic Liver Disease; FBG: Fasting Blood Glucose; LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; VAS: Visual Analog Scales; FBC: Full Blood Count; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; BMI: Body Mass Index; WC: Waist Circumference; HC: Hip Circumference; WHR: Waist Hip Ratio; FFQ: Food Freq...

Purpose: To investigate the effectiveness of homeopathic combination remedy compared with standard maintenance therapy for the treatment of dengue fever. Method: A total of 50 patients with dengue fever were divided into two equal groups. Group 1 was treated with homeopathic combination remedy for consecutive 6 days while standard maintenance therapy was similarly given to Group 2 patients. The...

Patients who are acutely unwell with suspected vaccine induced immune thrombocytopenia and thrombosis (VITT) should be referred immediately to the emergency department, says new rapid guidance from National Institute for Health Care Excellence (NICE).1 However, a full blood count performed in primary care if patient is not same day results can obtained. If these tests show low platelet departm...

Background : Meningitis is more common during the neonatal period than other periods of life and has a prevalence of one in 1000 live births. The similarity of its clinical manifestations with other infectious diseases makes it difficult to diagnose. The aim of the current study was to determine the relationship between age, sex, clinical signs and symptoms and laboratory test results of ne...