The ripened fruits of Schisandra chinensis (Turcz.) Baill., called Schisandrae Chinensis Fructus, are commonly used in traditional herbal medicine with a long history. The lignan constituents, especially the dibenzocyclooctadiene-type lignans, are mostly responsible for the biological and pharmacological effects of this herbal medicine. In this paper, a new micellar electrokinetic capillary chr...

BACKGROUND Japanese herbal medicines can be used as alternatives to estrogen therapy and are sometimes prescribed for menopausal syndrome because they have fewer side effects and are associated with better compliance than estrogen therapy, but little is known about the pharmacological mechanisms of such treatments. This study aimed to explore the mechanisms responsible for the estrogen-like eff...


 Purpose: To study the pharmacokinetics of morroniside (MR) and loganin (LG) in rats after oral administration raw wine-processed Corni fructus by UPLC-QqQ-MS/MS.
 Methods: Arctiin (AT) was used as internal standard, plasma or tissue samples were extracted twice using ethyl acetate. Electrospray ionization (ESI) negative ion mode used, multiple reaction monitoring (MRM) set acquisiti...

Red ginseng contains many bioactive constituents, including various ginsenosides that are believed to have antioxidant, immunostimulatory, and anti-aging activities. Yet, no controlled human study has explored its effects on photoaged skin. This study determined whether long-term intake of a red ginseng extract-containing Torilus fructus and Corni fructus mixture reduces facial wrinkles and inc...

2*-Deoxycoformycin (dCF) as a single agent hasbeenreported tobe lesseffectiveagainst myeloid than against lymphoid malignancies in clinical trials. However, previous studies have shown that in the presence of 2*-deoxyadenosine (dAd), human monocytoid leukemia cell lines are much more sensitive to dCF with regard to the inhibition of cell proliferation. Thus, dCF might be useful for treating mon...

We investigate the prevalence, specificity and possible aetiology of Disinhibited Attachment Disorder (DAD) in adopted children without a history of institutional care. Sixty children adopted from UK out-of-home care (AD; mean age 102 months, 45 % male); 26 clinic-referred children with externalizing disorder (ED; mean age 104 months, 77 % male) but no history of maltreatment or disrupted care;...

Risk assessment of polycyclic aromatic hydrocarbons (PAHs) contaminated soil and source apportionment require accurate analysis of the concentration of each PAH congener in the soil. However, determination of low level PAH congeners in soil is difficult because of similarity in the chemical properties of 16 PAHs and severe matrix interferences due to complex composition of soils. It is therefor...

The combination of Herba Epimedii and Fructus Ligustri Lucidi has been used to treat osteoporosis for almost 50 years by Professor Shizeng Li, a famous doctor of traditional Chinese medicine (TCM). However, it is unclear whether the combination of the effective constituents of the two herbs may have a protective influence on the skeleton. In the present study, we investigated the effects of the...

Perillae fructus (perilla seed) is a traditional medicinal herb used to treat bronchial asthma in Oriental medical clinics. ST36 is one of the most widely used acupuncture points, particularly for immune system regulation. Injection of an herbal extract into an acupuncture point (herbal acupuncture) is a therapeutic technique combining both acupuncture and herbal treatment. Perillae fructus ext...

OBJECTIVE To investigate the breeding rate and breeding density of Carpoglyphus lactisin stored Fructus Jujubaein Anhui, China in order to provide a scientific basis for prevention of Carpoglyphus lactis (C. lactis)from spoiling the dried fruit of such category. METHODS By the breeding nature of C. lactis,we collected samples of Fructus Jujubae, which were kept over 6 months in general, from ...