When frozen embryos are publically debated in the United States, they are most often positioned as having two possible future trajectories: (1) as individual humans and (2) as contributors to stem cell research. Long-term embryo accumulation threatens both of these futures. An accumulated embryo is stuck in a clinic, held back from having an individual future or from contributing to science. Th...

INTRODUCTION We report the fi rst successful preimplantation genetic diagnosis (PGD) for Hb Bart's hydrops fetalis in Singapore, involving both fresh and frozen embryo replacement cycles. CLINICAL PICTURE Two couples who were carriers of the Southeast Asian type double gene deletion (--(SEA) deletion carriers) requested for PGD. Couple A had 2 previous affected pregnancies, while couple B hav...

background:   objective: the aim of our study was to assess the effect of storage duration of frozen embryo on art outcome.   materials and methods: in this retrospective study the data of 651 frozen-thawed embryo transfer cycles were assessed over a 36-months period. our patients were categorized according to storage time of freeze. group i: less than 90 days, group ii: between 90-365 days. gr...

STUDY QUESTION Is endometrial thickness measured prior to embryo transfer associated with placenta praevia? SUMMARY ANSWER Following IVF, the risk of placenta praevia is increased 4-fold in women with an endometrial thickness of >12 mm compared with women with an endometrial thickness of <9 mm. WHAT IS KNOWN ALREADY Placenta praevia is a serious complication of pregnancy with adverse matern...

BACKGROUND Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have been reported to improve the quality of cleavage stage embryo evaluation during fresh culture, possible advantages in the evaluation of cryopreserved embryos have been scarcely ex...

USING EPIDIDYMAL AND TESTICULAR SPERM FROM AZOOSPERMIC MEN: THE CLEVELAND CLINIC EXPERIENCE Mehmet Oder, Ramadan A Saleh, Namita Kattal, Mohamed A Bedaiwy, Anthony J Thomas, Ashok Agarwal, Cleveland Clinic Foundation Objective: Sperm retrieval from testis and epididymis, combined with ICSI, has significantly enhanced the chances of azoospermic men to father their own genetic offspring. The impa...

Translocation is one of the more common structural rearrangements of chromosomes, with a prevalence of 0.2%. The two most common types of chromosomal translocations, Robertsonian and reciprocal, usually result in no obvious phenotypic abnormalities when balanced. However, these are still associated with reproductive risks, such as infertility, spontaneous abortion and the delivery of babies wit...

Abstract Background Frozen embryo transfer procedure is becoming more common in assisted reproduction technology. The effect of this technology still not yet well studied developing countries with limited resources, including Indonesia. This study explores the clinical outcomes between frozen and fresh transfer-conceived children aged 0–3 years Results participants were divided into ( n = 30) g...

Background: Controlled ovarian stimulation (COS) has been shown to advance endometrial maturation and affect adversely implantation in assisted reproduction technology (ART) cycles. It has been reported that there is a better embryo-endometrium synchrony in frozenthawed embryo transfer (FET) cycles than fresh embryo transfer (ET) cycles. The Background of this study was to compare ongoing pregn...