Performance on the Twenty Questions task has been assumed to be deficient in those with frontal lobe damage, although few studies have specifically examined this. In the present study, 88 participants with frontal lobe epileptic dysfunction were assessed on this task, as were 57 participants with temporal lobe epileptic disturbance and 28 participants with no evidence of any neurological damage...

The definitive structure and functional role of the inferior fronto-occipital fasciculus (IFOF) are still controversial. In this study, we aimed to investigate the connectivity, asymmetry, and segmentation patterns of this bundle. High angular diffusion spectrum imaging (DSI) analysis was performed on 10 healthy adults and a 90-subject DSI template (NTU-90 Atlas). In addition, a new tractograph...

Previous research with older adults suggests that the frontal lobes and the medial temporal lobes play an important role in recognition memory. The goal of this study was to investigate the impact of high/low frontal lobe and medial temporal lobe status in younger adults’ recognition memory performance. Twenty-four college-aged women completed a neuropsychological battery and a recognition memo...

AIMS Scalp-EEG interictal epileptiform discharges (IEDs) may be less predictive of the outcome of frontal lobe epilepsy surgery than of temporal lobe epilepsy surgery. We identified factors associated with the location of scalp-EEG IEDs in intractable frontal lobe epilepsy. METHODS Ten factors were assessed in a retrospective review of 53 patients with either concordant (frontal lobe seizure ...

BACKGROUND AND PURPOSE Most studies on post-stroke depression (PSD) have focused on a certain time point after stroke instead of the time course of PSD. The aim of this study was to determine the relationship between frontal lobe lesions, course of PSD over a year following the stroke onset, and the 1-year prognosis in patients with first-ever ischemic stroke. METHODS A total of 1067 patients...

AIM Planning disorders have been observed in people with frontal lobe lesions for many decades. There's also growing body of evidence of frontal dysfunction in people with schizophrenia. The aim of this study is to compare the planning abilities in men with schizophrenia, men with localized frontal lobe lesions and healthy men. METHOD A sample of 90 men participated in the study. They were di...

Previous research has indicated the importance of the frontal lobe and its 'executive' connections to other brain structures as crucial in explaining primate neocortical adaptations. However, a representative sample of volumetric measurements of frontal connective tissue (white matter) has not been available. In this study, we present new volumetric measurements of white and grey matter in the ...

The frontal lobes are widely implicated in logical reasoning. Recent neuroimaging studies suggest that frontal lobe involvement in reasoning is asymmetric (L>R) and increases with the presence of familiar, meaningful content in the reasoning situation. However, neuroimaging data can only provide sufficiency criteria. To determine the necessity of prefrontal involvement in logical reasoning, we ...