Chitosan was used for nanoencapsulation of Lactobacillus acidophilus as probiotic bacteria. In vitro experiments were done with the objective of investigating the survival of the bacteria cells in gastro-intestinal conditions. The results demonstrated that the size of chitosan nanoparticles noticeably increases by increasing chitosan concentration from 0.05 to 0.5 g/mL. Encapsulation of the cel...

Multiple myeloma (MM) is the second most common hematological malignancy. The introduction of novel agents such as thalidomide, bortezomib, and lenalidomide in more recent years has significantly improved the response rate, progression‐free survival (PFS), and overall survival (OS) of MM patients.[1,2] However, alongside these benefits, a significant increased risk of developing secondary prima...

Prostate cancer is a common malignancy worldwide, and in Canada, it is the most frequently diagnosed cancer in men. The stratification of prostate cancer into risk categories has allowed for improved counselling of patients and provides guidance for treatment selection. However, the exact definition of high-risk prostate cancer remains controversial, and that lack of consensus remains a barrier...

The potential impact that the intratumoral expression level of dihydropyrimidine dehydrogenase (DPD) has on chemotherapy sensitivity and long-term survival for gastric cancer (GC) patients remains controversial; therefore, this study seeks to clarify this issue. Our meta-analysis was performed using Review Manager (RevMan) 5.3 software. In vitro drug sensitivity tests, correlation coefficients ...

background: considering the ease of administration of capecitabne instead of infusional 5fu for concurrent  radiochemotherapy (rct) of rectal cancer, the use of capecitabine has increased significantly in our radiation oncology department in the past years. thus we decided to compare the safety and survival with these 2 drugs by a retrospective review. methods: files of all patients receiving r...

introduction: lymphoma may involve the gastrointestinal tract either primarily or as a manifestation of extensively disseminated systemic disease. stomach being the most frequent site of primary gastroin-testinal lyphoma, followed by the small bowel and colon respectively (1&2&3). for diagnosis of pi-mary small intestinal lymphoma (psil), one most satisfies the criteria specified by dawson and ...

introduction: breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. the occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasion. the aim of this study was to examine the presence of keratin-19 mrn...