Information on exposure and reaction to sunlight, together with the history tf exposure to fluorescent lighting, was elicited by postal questionnaire. Case-control analyses from 58 patients with malignant melanoma, 182 matched controls and 151 unmatched controls showed associations between malignant melanoma and (i) bouts of painful sunburn, (ii) reaction of untanned skin to sunlight, and (iii)...

A frequent immune-related adverse event of checkpoint-inhibitor (CPI) treatment, which manifests as depigmented spots on the skin is known Vitiligo-like depigmentation (VLD). The aim this study was to further characterize clinical, biological and prognostic features melanoma patients with VLD under CPI-treatment explore whether they exhibit a characteristic immune response profile in peripheral...

BACKGROUND Melanocytic nevi (moles) and freckles are well known biomarkers of melanoma risk, and they are influenced by similar UV light exposures and genetic susceptibilities to those that increase melanoma risk. Nevertheless, the selective interactions between UV exposures and nevus and freckling genes remain largely undescribed. METHODS We conducted a longitudinal study from ages 6 through...

Abstract Channel segregation – known as freckle is one of the most complex defects which severely limit mechanical properties investment cast single-crystal turbine blades. The phenomenon induced by thermal-solutal-fluid flow instability during solidification process; it therefore important to gain better understanding fluid flow, heat transfer and species transport casting process. In this wor...

Background: Determination of the prevalence of diseases is an important step in health programs. Objective: To determine the prevalence of skin diseases in primary school students in Ahwaz. Patients and Methods: This cross-sectional study was done in March and April 1995 (Esfand 1373, Farvardin 1374) in Ahwaz. 3000 male and 3000 female primary school students were examined for the presence of s...

OBJECTIVE To investigate risk factors for lentigo maligna melanoma (LMM) compared with superficial spreading melanoma (SSM). DESIGN Population-based case-control study in Queensland, Australia. SETTING General community. PARTICIPANTS Population-based sample of 49 patients with LMM and 141 with SSM (in situ or invasive) aged 14 to 86 years at diagnosis in 1979 and 1980 and 232 control subj...

BACKGROUND Ichthyosis is an infrequent clinical entity worldwide (1:300,000 births). When diagnosed in a newborn, two forms can be identified: collodion baby and its most severe form, harlequin fetus or maligna keratoma. In both cases, clinical manifestations are thick and hard skin with deep splits. The splits are more prominent in the flexion areas. CASE We report a case of a 4- day-old bab...

BACKGROUND Dermoscopy has led to an improvement in diagnosing malignant melanoma (MM). Sunless tanning agents containing dihydroxyacetone (DHA) could lead to a decrease in ultraviolet exposure, decreasing the risk of MM. Importantly, DHA has been reported to change dermoscopic features and could thus endanger diagnostic improvement in dermoscopy. OBJECTIVES To investigate whether the use of D...

Melanosis of the urinary bladder is very rare. It is characterized by the deposition of melanin within the vesical urothelium and/ or lamina propria without the presence of melanocytes [1]. It is a distinct pathological entity in its own right and is not directly related to other melanotic lesions such as melanocytic naevus, lentigo maligna or malignant melanoma. At present, melanosis of the bl...