INTRODUCTION The pattern of glucose levels during an oral glucose tolerance test (OGTT) may be useful for predicting diabetes or cardiovascular disease (CVD). Our aim was to determine whether the time to peak glucose during the OGTT is associated with CVD risk scores and diabetes. METHODS Individuals with impaired fasting glucose (IFG) were enrolled in this observational study. Participants w...

In their thoughtful and provocative article ‘Are the Framingham and PROCAM coronary heart disease risk functions applicable to different European populations? The PRIME Study’, Drs Empana and colleagues astutely conclude that the answer is neither simple nor straightforward. On the one hand, they conclude that the Framingham (from the United States) and PROCAM (from Germany) risk functions over...

OBJECTIVE To evaluate the performance of the QRISK2 score for predicting 10-year cardiovascular disease in an independent UK cohort of patients from general practice records and to compare it with the NICE version of the Framingham equation and QRISK1. DESIGN Prospective cohort study to validate a cardiovascular risk score. SETTING 365 practices from United Kingdom contributing to The Healt...

PURPOSE/INTRODUCTION The Canadian Hypertension Education Program (CHEP) has identified blood pressure (BP) control as a key target for an overall reduction in cardiovascular disease risk. The POWER survey (Physicians' Observational Work on Patient Education According to their Vascular Risk) used Framingham methodology to investigate the impact of an angiotensin-receptor-blocker-based regimen on...

Purpose: The new non-invasive arterial stiffness indices, velocity pulse index (AVI) and pressure volume (API) are known to be associated with cardiovascular disease risk. present study aimed examine the “dose-response” associations between AVI, API Framingham risk score (FCVRS). Methods: This survey included individuals indices collected at age 18 years older. We used Pearson’s correlation coe...