This paper presents a mathematical deterministic adaptive distance protection formulation for UPFC compensated transmission lines. The proposed formulation is developed using a phase component approach and considers and compensates for various UPFC operation conditions and non-zero fault resistances. The proposed methodology is completely adaptive and independent of system characteristics (such...

The aim of the present study was to investigate the sleep promoting effect of BR-16A, a polyherbal formulation along with GABAergic drugs. Pentobarbitone-induced hypnosis test was used as an animal model to explore its role in sleep. Pentobarbitone produces quick the sleep latency (onset) and prolongation of total sleep time (duration). Seep latency and total sleep time were used as parameters ...

The present study was focused on formulating and evaluating clarithromycin (CLR) containing niosomal formulation for in vitro and in vivo pharmacokinetic behavior. Niosomal formulations (empty and drug loaded) were prepared by using different ratio of surfactant (various Span grades 20, 40, 60, and 80) and cholesterol by thin film hydration method and were evaluated for in vitro characteristics...

a gradient reversed-phase high performance liquid chromatography (hplc) method was developed for the assay of cetrorelix acetate, a synthetic decapeptide with gonadotropin-releasing hormone (gnrh) antagonistic activity used in infertility treatment. the hplc method, which is used to determine cetrorelix in bulk and pharmaceutical dosage forms, was validated per ich guidelines. the chromatograph...

Objective: Investigation of in vitro/in vivo behaviour of fast-dissolving tablets containing solid dispersions of oxcarbazepine is the focus of the present research work. Methods: The effect of various hydrophilic polymers on the aqueous solubility of oxcarbazepine was studied. Polyethylene glycol 6000 carrier was selected and solid dispersions were prepared by various methods. A total of nine ...

The aim of this study was to assess the effects of processing parameters on the release of solid dispersion formulation from a fast dissolving tablet dosage form. Graphical and mathematical analysis such as the response surface methodology (RSM) and multiple response optimizations utilizing the polynomial equation were used to search for the optimal formulation and to quantify the effect of eac...

omega-3 fatty acids (fas) have been shown to prevent cardiovascular disease. the most commonly used omega-3 fatty acids like eicosapentaenoic acid (epa) and docosahexaenoic acid (dha) are highly vulnerable to oxidation and therefore, have short shelf life. recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 fas. several methods could be implemented to prepar...

the aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

Overcrowding of broiler chicks due to lack of space induces harmful effects which act as predisposing factor in the reduction of production and performance in poultry. Supplementation of antistressor products can ameliorate adverse effect of various stressors in poultry. An experiment was designed by inducing overcrowding stress and its management by supplementation of polyherbal antistressor, ...