Results We evaluated 80 questionnaires answered by physicians (38 male) from various specialties. The majority of them were between 20 and 30 years-old. The most frequent specialties were Orthopedics and Pediatrics (22.5%). The graduate year was between 2005 and 2013 in 62.5%. Forty-six had already treated patients with anaphylaxis. The most frequent triggers were: drugs (22), food (20), insect...

BACKGROUND The diagnosis of anaphylaxis is based on clinical history since no reliable biological marker is currently available to confirm the diagnosis. OBJECTIVE It was the aim of this study to determine sequential serum tryptase concentrations during anaphylaxis and to evaluate its potential as a diagnostic marker. METHODS We performed a prospective study including patients with acute an...

Introduction: Anaphylaxis is a predominantly childhood disease. Most of the literature on anaphylaxis has emerged from Western countries. This study aimed to describe the incidence, triggers and clinical presentation of anaphylaxis among children in Singapore, look for predictors for anaphylaxis with severe outcomes, and study the incidence of biphasic reactions. Materials and Methods: We retro...

Recent findings Patient risk factors and co-factors that amplify anaphylaxis have been documented in prospective studies. The global perspective on the triggers of anaphylaxis has expanded. The clinical criteria for the diagnosis of anaphylaxis that are promulgated in the Guidelines have been validated. Some aspects of anaphylaxis treatment have been prospectively studied. Novel investigations ...

BACKGROUND Despite the importance of anaphylaxis, little information is available on its clinical features. OBJECTIVE To evaluate the clinical and allergologic features of anaphylaxis in children referred to the allergology and immunology unit of A. Meyer Children's Hospital (Florence, Italy) from 1994 to 1996. RESULTS Ninety-five episodes of anaphylaxis occurred in 76 children (50 boys and...

BACKGROUND Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic diseases recently. This study aimed at exploring whether Clostridium butyricum CGMCC0313-1 (C. butyricum) can reduce β-lactoglobulin(BLG)-induced intest...

BACKGROUND Food allergy is the most common cause of anaphylaxis outside the hospital setting. OBJECTIVE We sought to determine the rate, circumstances, and risk factors for repeated doses of epinephrine in the treatment of food-induced anaphylaxis in children. METHODS Anonymous questionnaires were distributed to families of children with food allergies during allergy outpatient visits to a ...

Anaphylaxis is currently classified as an immunologically triggered response with reactions that are IgE-mediated and reactions that are not IgE-mediated. This immunologically mediated phenomenon can result in various clinical manifestations, including decreased blood pressure, generalized skin inflammation, such as hives and pruritus, and respiratory symptoms, such as wheezing or bronchospasm....

BACKGROUND There are no epidemiological data available on anaphylaxis in German adults and so far there has been no consensus on when to diagnose anaphylaxis, mainly due to a lack of generally accepted diagnostic criteria. Recently, an international expert group addressed this issue by suggesting new diagnostic criteria for anaphylaxis. We addressed the usefulness of the suggested diagnostic cr...