Thyrotropin (TSH) is thought as a risk factor for thyroid cancer. However, the effect of serum TSH might depend on histological types of thyroid cancer. We searched for related studies including serum TSH as an exposure and thyroid cancer as a result in PUBMED, EMBASE and Chinese National Knowledge Infrastructure up to April 21, 2016. This meta-analysis included 22 articles with 53,538 particip...

AIM To stratify the malignancy risks in thyroid nodules in a tertiary care referral center using the Bethesda system. METHODS From January, 2012 to December, 2014, a retrospective analysis was performed among 1188 patients (15-90 years) who had 1433 thyroid nodules and fine-needle aspiration at Prince Sultan Military Medical City, Saudi Arabia. All thyroid cyto-pathological slides and ultra s...

The molecular biology of follicular cell growth in thyroid nodules is still poorly understood. Because gain-of-function (activating) mutations of the thyroid-stimulating hormone receptor (TShR) and/or Gs alpha genes may confer TSh-independent growth advantage to neoplastic thyroid cells, we searched for somatic mutations of these genes in a series of hyperfunctioning and nonfunctioning follicul...

1 of 2 DESCRIPTION A 55-year-old woman, resident in an iodine-suffi cient area, had a diffuse goitre for 25 years. She presented with a rapidly increasing swelling in the right frontal region for 3 months and increasing thyroid gland enlargement for 4 years. On examination, she had a diffuse, fi rm goitre (grade IV) with multiple tattoo marks and no cervical adenopathy. The swelling in the righ...

Around 1500 new cases of thyroid cancer are diagnosed each year in the United Kingdom, being responsible for around 320 deaths annually. Detecting recurrent thyroid carcinoma is important for the speedy imposition of treatment regimens, but occasionally detecting subsequent disease can be problematic. Bone is the commonest site for distant thyroid carcinoma metastases, but other sites such as t...

Around 1500 new cases of thyroid cancer are diagnosed each year in the United Kingdom, being responsible for around 320 deaths annually. Detecting recurrent thyroid carcinoma is important for the speedy imposition of treatment regimens, but occasionally detecting subsequent disease can be problematic. Bone is the commonest site for distant thyroid carcinoma metastases, but other sites such as t...

OBJECTIVES The aim of this study was to examine the expression of the N-myc downstream-regulated gene 1 protein in benign and malignant lesions of the thyroid gland by immunohistochemistry. INTRODUCTION N-myc downstream-regulated gene 1 encodes a protein whose expression is induced by various stimuli, including cell differentiation, exposure to heavy metals, hypoxia, and DNA damage. Increased...

Thyroid carcinoma is uncommon but accounts for roughly 95% of all cancers of the endocrine system (1). The "well-differentiated" thyroid tumors include the papillary, follicular, and Hurthle cell subtypes. Although the management of these tumor types generally is similar, important diagnostic and clinical differences do exist (2). We present a case of follicular thyroid carcinoma with spinal me...

Vascular invasion is characteristic for follicular carcinoma of the thyroid and distant metastasis common. Spinal cord compression due to metastases differentiated as initial presentation an extremely rare condition. We report a case asymptomatic metastatic cancer which presented with spinal compression. This patient metastasized narrowing airway posed many challenges anesthetist.