Amorfrutins are isoprenoid-substituted benzoic acid derivatives, which were found in Amorpha fruticosa L. (bastard indigo) and in Glycyrrhiza foetida Desf. (licorice). Recently, amorfrutins were shown to be selective activators of the nuclear receptor PPARγ. Here, we investigated the effects and PPARγ-based mechanisms of reducing inflammation in colon cells by treatment with amorfrutins. In TNF...

in this experiment, the chemical composition of the essential oils obtained from ferula assa-foetida oleo-gum resin collected from two different sites of yazd province (tabas and yazd) in the center of iran, were identified. the gas chromatography mass-spectroscopy (gc/ms) data showed that the qualitative composition of the components appeared to be constant in two different regions. moreover, ...

medical plants are adapted to different kinds of dormancy to survive in the worst situations. regarding to ecological viewpoint, this kind of adaptation is very important in respect to restriction of genetic draft and decrease of genetic resource of medicinal plants. this leads to plant survival even after prolonged drought. since some of them are endangered species and in the other hand increa...

introduction: considering the prevalence of epilepsy and the failure of available treatments for many epileptic patients, finding more effective drugs in the treatment of epilepsy seems necessary. oxidative stress has a special role in the pathogenesis of epileptic syndrome. therefore, in the present study, we have examined the anti-epileptic and anti-oxidant properties of the ferula assa foeti...

Introduction: Considering the prevalence of epilepsy and the failure of available treatments for many epileptic patients, finding more effective drugs in the treatment of epilepsy seems necessary. Oxidative stress has a special role in the pathogenesis of epileptic syndrome. Therefore, in the present study, we have examined the anti-epileptic and anti-oxidant properties of the Ferula Assa Foeti...

background quorum sensing is a microbial cell-to-cell communication process. quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. gram-positive and gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. objectives the goal of this study was to assess the impact of subinhibitory concen...

Introduction The earthworm coelomic fluid (ECF) has shown proven antiproliferative effect against breast, liver, gastrointestinal, and brain cancer, but it is least explored in oral cancer. The present in vitro study is an attempt to investigate the antiproliferative activity of ECF on oral cancer cell line squamous cell carcinoma (SCC)-9. Materials and Methods ECF was collected from the spec...

A novel antimicrobial short peptide was purified from earthworm (Eisenia foetida) by a five-step protocol including ammonium sulfate precipitation, ultrafiltration, DE-52 ion exchange chromatography, Sephadex G-10 column chromatography, and C-18 reversed-phase HPLC techniques. The purified peptide was applied to the MALDI-TOP MS to determine the molecular mass and was also subjected to TOF MS-M...