Niacin lowers serum cholesterol, low-density lipoprotein, and triglycerides, and it raises high-density lipoprotein. However, most patients experience cutaneous warmth and vasodilation (flush). Acetylsalicylic acid (ASA) can reduce this flush, presumably by decreasing prostaglandin D(2) (PGD(2)) release from macrophages. Here, we show that methylnicotinate induces significant PGD(2) release fro...

Benefiting from the rapid development of convolutional neural networks, performance car license plate detection and recognition has been largely improved. Nonetheless, most existing methods solve problems separately, focus on specific scenarios, which hinders deployment for real-world applications. To overcome these challenges, we present an efficient accurate framework to tasks simultaneously....

To investigate the influence of end-plate stiffeners on the initial rotational stiffness of extended end-plate internal joints, an experimental program was carried out to investigate the rotational behavior of the joints. Two finite element methods (FEMs) were proposed using ABAQUS software. The stress distribution, plastic development, and deformation characteristics of extended end-plate join...

PURPOSE To investigate the clinical efficacy of low-dose chlormadinone acetate (CMA) in prostate cancer patients who suffer from hot flushes that is a major side effect of androgen deprivation therapy. METHODS Our study included 32 prostate cancer patients who had severe hot flush after undergoing hormone therapy for more than 3 months. The average age of the patients was 72.5 years. In the b...

Valves are usually used in conjunction with large water-tower storage structures. Large pipes carry water from the storage tower to the flush gutter. Valves are used at appropriate locations in the pipeline to control flush water flow to individual gutters. Figure 1 is a schematic layout of a flush system using storage towers, pipelines and valves to flush several gutters. Use of multiple, inte...

Headspace oxygen in sample vial for the purge-and-trap dynamic headspace/gas chromatography method oxidizes meat if held hours before purging, influences volatile profiles, and misrepresents the true composition of volatiles. Helium flush and helium flush plus oxygen absorber were used to eliminate residual oxygen and minimize oxidative changes in meat during sample holding time. Both helium fl...