BACKGROUND Speech segmentation is one of the initial and mandatory phases of language learning. Although some people with aphasia have shown a preserved ability to learn novel words, their speech segmentation abilities have not been explored. AIMS We examined the ability of individuals with chronic aphasia to segment words from running speech via statistical learning. We also explored the rel...

IMPORTANCE Grammatical comprehension difficulty is an essential supporting feature of the non-fluent/agrammatic variant of primary progressive aphasia (naPPA), but well-controlled clinical measures of grammatical comprehension are unavailable. OBJECTIVE To develop a measure of grammatical comprehension and examine this comparatively in PPA variants and behavioural-variant frontotemporal degen...

OBJECTIVE To determine factors associated with good responses to speech therapy combined with transcranial direct current stimulation (tDCS) in aphasic patients after stroke. METHOD The language function was evaluated using Korean version of Western aphasia battery (K-WAB) before and after speech therapy with tDCS in 37 stroke patients. Patients received speech therapy for 30 minutes over 2 t...

Few studies have directly compared the clinical and anatomical characteristics of patients with progressive aphasia to those of patients with aphasia caused by stroke. In the current study we examined fluent forms of aphasia in these two groups, specifically semantic dementia (SD) and persisting Wernicke's aphasia (WA) due to stroke. We compared 10 patients with SD to 10 age- and education-matc...

Within primary progressive aphasia the logopenic variant remains less understood than the two other main variants, namely semantic and non-fluent progressive aphasia. This may be because of the relatively small number of explored patients and because of the lack of investigations with a comprehensive three-level characterization of cognitive, brain localization and biological aspects. The aim o...

We described a 56-years-old man with a diagnosis of "non-fluent primary progressive aphasia" (NfPPA). An accurate neuropsychological, neurological and neuroimaging evaluation was performed in order to assess clinical and behavioural features of the patient. From a neuropsychological point of view, the patient showed a typical cognitive profile of subjects affected by NfPPA: a prominent language...

The vulnerability of time reference, either marked by means of verbal morphology or by adverbs, has been established in an extensive array of languages in agrammatic aphasia. Recent studies (Bastiaanse, 2008; Lee et al., 2008; Nanousi et al., 2006; Martínez-Ferreiro, 2010; Yarbay Duman and Bastiaanse, 2009; among others) have determined that far from being general, the observed deficit is sensi...

We report five patients with a stereotyped clinical syndrome characterized by fluent dysphasia with severe anomia, reduced vocabulary and prominent impairment of single-word comprehension, progressing to a stage of virtually complete dissolution of the semantic components of language. A marked reduction in the ability to generate exemplars from restricted semantic categories (e.g. animals, vehi...