The gingiva is frequently the site of localised growths that are thought to be reactive rather than neoplastic. Many these lesions difficult identify clinically and can only identified as a distinct entity based on typical consistent histomorphology. One such lesion peripheral ossifying fibroma. It has been described using various synonyms arise from periodontal ligament, which accounts for app...

Among various types of gingival enlargements, Peripheral ossifying fibroma (POF) is a rare entity, which is nonneoplastic in nature and arises due to trauma, plaque, calculus, restorations and dental appliances. The term peripheral ossifying gingival growth was coined by Eversole and Rovin. Various synonyms are used for this gingival growth, like peripheral cementifying fibroma, ossifying fibro...

desmoplastic fibroma is a rare, locally aggressive, benign lesion. a case of desmoplastic fibroma of left side of mandible is reported. the lesion presented as painless mass in left posterior portion of mandible of a 7-year-old girl. histologically the lesion was composed of interlacing fascicles of benign appearing fibroblast in a varying ground substance of collagenous tissue. in this report,...

Verna, John E. (University of Minnesota, Minneapolis). Cell-culture response to fibroma virus. J. Bacteriol. 89:524-528. 1965.-Three established rabbit cell lines (Minnesota CRP, RbK, and RbH) were infected with Shope's rabbit fibroma virus (Patuxent strain). The responses of the cell lines to virus infection differed from one another. Minn. CRP cells produced plaques (1 to 2 mm) on the 4th or ...

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated wi...

The clinical and pathological features of six cases of desmoplastic fibroma of bone are presented. Desmoplastic fibroma is rarely seen as a primary tumour of bone; when it does occur the sites of predilection are the long bones, but other sites such as the scapula and os calcis can be involved. Radiographically the lesion tends to expand the bone from within; it is well-demarcated and lytic, of...

Giant Cell Fibroma (GCF) was described as a new entity of fibrous hyperplastic soft tissue. It seems that stimulus from an unexplained origin can have a role in its etiology. Histopathologically GCF is consisted of multinucleated fibroblasts that have oval shape nuclei within the eosinophilic cytoplasm. Surgical excision is the treatment of choice and recurrence is very rare. Here we report a c...

The virus-induced papillomas of cottontail as well as domestic rabbits regress completely within a few weeks when exposed to 5,000 r of x-ray irradiation. The x-rays do not immediately kill the papilloma cells, but lead to death by inhibiting cellular division and producing pathological changes in the cells which then continue to differentiate. The virus associated with the growths, however, no...

A series of nine cases of fibroma of tendon sheath is described including details of the ultrastructural features of two cases. The series was composed of lesions from six males and three females with a mean age of 38 yr. The most common site of involvement was the hand (including fingers) and the mean greater diameter was 19 mm. Typically the tumours were lobulated and microscopically there wa...

Seven cases of recurring digital fibroma were seen over a 35-year period. All demonstrated the classical clinical, macroscopic, and microscopic features of this distinct tumour, including the pathognomonic round, eosinophilic cytoplasmic inclusion bodies. Ultrastructurally, all seven cases were confirmed to be myofibroblastic in nature, and the morphology and intracellular topography of the inc...