background: assessment of myocardial function is essential in heart disease, but in regard to systolic and diastolic functions such evaluation has limitation. ejection fraction is difficult to assess in abnormally-shaped ventricles, and diastolic inflow velocity pattern may be fused because of tachycardia.   objective: a myocardial performance index (mpi) or tei index has been developed for adu...

Isolated cardiac muscle techniques and studies of the chronically instrumented fetal lamb heart were employed to evaluate the ability of fetal myocardium to exhibit poststimulation potentiation. Isometric tension development and the response to paired electrical stimulation were significantly reduced in isolated fetal ventricular myocardium when compared to the adult (P less than 0.001). As in ...

experimental and clinical studies have shown that intracoronary transplantation of autologous bone marrow mesenchymal stem cells (bmscs) has resulted in regenerated infarcted myocardium and improved left ventricular (lv) function.the aim of this pilot study was to assess the benefical effectsof intracoronary transplantation of bmsc in patients with oldmyocardial infarction (omi). autologous bms...

outine fetal arrhythmia assessment typically involves the se of echocardiographic modalities that demonstrate mehanical events from which electrophysiological events are nferred (1). While M-mode and Doppler-based techniques ave been used successfully to diagnose third-degree atrioentricular block (AVB), second-degree AVB, and, more ecently, first-degree AVB, our evaluation has been limited o a...

The goal of this study was to test the hypothesis that the relative amounts of the cardiac myosin heavy chain (MHC) isoforms MHC-alpha and MHC-beta change during development and transition to heart failure in the human myocardium. The relative amounts of MHC-alpha and MHC-beta in ventricular and atrial samples from fetal (gestational days 47--110) and nonfailing and failing adult hearts were de...

Su, JUDY Y., AND WILLIAM F. FRIEDMAN. Comparison of the responses of fetal and adult cardiac muscle to hypoxia. Am. J. Physiol. 224(6): 1249-1253. 1973.-The responses of cardiac tissue isolated from fetal and adult sheep were compared after selective inhibition of aerobic and anaerobic metabolism. The frequency of contraction of adult right atria was significantly more depressed by oxygen depri...

The M-mode echocardiogram can be obtained in the developing human fetus from around the 16th week of gestation until term. Errors in interpretation of the M-mode echocardiogram can be avoided by concurrent two dimensional fetal cardiac examination. The pattern of motion of the mitral, tricuspid, aortic, and pulmonary valves and ventricular wall motion can be studied. Motion of the foramen ovale...

BACKGROUND Precise diagnosis of cardiac arrhythmias in the fetus is crucial for a managed therapeutic approach. However, many technical, positional, and gestational age-related limitations may render conventional methods, such as M-mode and Doppler flow methodologies, or newer techniques, such as fetal electrocardiography or magnetocardiography, difficult to apply, or these techniques may be un...

We experienced a case with fetal cardiac tumor, which was diagnosed by prenatal ultrasonographic examination, and the diagnosis was confirmed after birth. A pregnancy woman of the 26th week of gestation was referred to our hospital for close examinations of fetal cardiac tumor. Ultrasonographic examinations revealed single homogeneous tumor with the diameter of 14 mm intracardiac space. The tum...