A study of 533 women with very low urinary oestriol excretion during the third trimester of pregnancy showed an incidence of major fetal malformations among their infants of 7-1% and a perinatal mortality rate of 14-6%. Thirteen of the malformations were cases of anencephaly, and 26 of the 78 perinatal deaths were due to or associated with major fetal malformations. The incidence of these compl...

Hypertensive disorders are one of the most common medical complications of pregnancy and a major cause of both maternal and fetal morbidity and mortalityand are one of the leading causes of maternal deaths.1-4 They can cause several dreaded complications such as eclampsia, disseminated intravascular coagulation, cerebral edema, liver failure and ante-partum hemorrhage. Maternal hypertension als...

BACKGROUND Intrauterine growth restriction (IUGR) is the single largest contributing factor to perinatal mortality in non-anomalous fetuses. Advances in antenatal and neonatal critical care have resulted in a reduction in neonatal deaths over the past decades, while stillbirth rates have remained unchanged. Antenatal detection rates of fetal growth failure are low, and these pregnancies carry a...

Objective: Trauma is the significant non-obstetrical cause of maternal mortality in women aged 35 years or younger. It is expected to complicate around 1 in 12 pregnancies and accounts for 46% of such deaths. In this study, we present our experience of trauma during pregnancy at a tertiary care hospital in Karachi.Methods: A standardized form was used to extract data from online records f...

Information from vital records is critical to identify and quantify health-related issues and to measure progress toward quality improvement and public health goals. In particular, maternal and infant mortality serve as important indicators of the nation's health, thereby influencing policy development, funding of programs and research, and measures of health care quality. Accurate and timely d...

A total of 5082 consecutive deliveries in Medical College Hospital, Kottayam during the period August 1992 to July 1993 constituted the study. Perinatal mortality rate (PMR) was 38.5 per 1000 total births and autopsy rate was 72%. More than 85% of perinatal deaths occured in low birth weight and preterm babies. Perinatal hypoxia and congenital anomalies were the leading causes in late fetal dea...

OBJECTIVE To evaluate the incidence of fetal dextrocardia, associated cardiac and extracardiac malformations, and outcome. DESIGN Retrospective echocardiographic study. SETTING Two tertiary centres for fetal cardiology. PATIENTS 81 consecutive fetuses with a fetal dextrocardia presenting at Guy's Hospital, London, between 1983 and 2003 and at Hôpital Robert Debré, Paris, between 1988 and ...

Objective: To evaluate the incidence of fetal dextrocardia, associated cardiac and extracardiac malformations, and outcome. Design: Retrospective echocardiographic study. Setting: Two tertiary centres for fetal cardiology. Patients: 81 consecutive fetuses with a fetal dextrocardia presenting at Guy’s Hospital, London, between 1983 and 2003 and at Hôpital Robert Debré, Paris, between 1988 and 20...