Natural products and dietary components have earlier been proven as potential chemoprotective agents, and continuous efforts are in progress to search for such new products. Gentamicin, an aminoglycoside antibiotic, is widely used for treating the infections caused by many gram negative bacteria. However, besides other unwanted effects, the drug causes tubular cell necrosis in the proximal conv...

OBJECTIVE The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is "Koma". In this research we tried to isolate and elucidate the structure of...

In this study we investigated the phytoconstituents Calluna vulgaris, Ferula hermonis and Tribulus terrestris, and then assessed their possible biological activities by using standard methods. A preliminary phytochemical investigation of the three extracts revealed the presence of alkaloids, flavonoids, proteins, lipids, phenolic compounds, saponins, sterols and amino acids. Three extracts show...

The intention of this study was to compare the different parts Tunisian Ferula communis via their fatty acids, essential oils and phenolic compounds. Results showed that lipid fraction fruits leaves characterized by predominance oleic acid. Erucic linoleic acids were most abundant in stems while palmitic flowers. F. defined four chemotypes, namely isoshyobunone/6-tert-butyl-4-methylcoumarin ste...

The main losses of tefestrol have been identified and the advantages disadvantages existing technology in production substance from aerial parts Ferula tenuisecta established. It was found that final product obtained by has a green color does not meet requirements Pharmacopoeia article. stage proposed extraction sum esters sesquiterpene alcohols part purification extract, allowing to subsequent...

8-p-Hdroxybenzoyl tovarol (TAW) is a germacrane-type sesquiterpenoid that can be isolated from the roots of Ferula dissecta (Ledeb.) Ledeb. In this study, the growth inhibitory effects induced by TAW were screened on some types of tumor cells, and the mechanism was investigated on TAW-induced growth inhibition, including paraptosis and autophagy in human cervical cancer HeLa cells. TAW-induced ...