BACKGROUND Increased estimated body iron stores have been recently suggested to be associated with increased risk of acute myocardial infarction (AMI); however the question of whether serum ferritin level as an indicator for estimating body iron is an independent risk factor for cardiac events is still questioned. In the present study, we assessed whether serum ferritin was associated with the ...

OBJECTIVES To validate the prognostic significance of preoperative serum iron metabolism parameters in non-metastatic colorectal cancer patients treated with curative resection.   Methods: We conducted a prospective cohort study in the Department of Surgical Oncology, WuXi 4th People's Hospital, WuxiChina, between  March 2010 and September 2013.  The relationships of serum iron metabolism param...

BACKGROUND Concern has been raised that high levels of ascorbic acid consumption may lead to potential adverse effects, such as vitamin B12 deficiency, iron overload, and kidney stones. OBJECTIVE To examine the relation of serum ascorbic acid level, which reflects intake, to serum vitamin B12 level, serum ferritin level, and kidney stones. METHODS We analyzed data collected on a random samp...

Elevated serum ferritin levels without a corresponding increase in tissue iron storage have been observed in patients with certain cancers. Increased synthesis of ferritin by cancer cells has also been reported. In order to see whether similar phenomena occurred in patients with neuroblastoma, we have screened serum ferritin levels in 58 children with neuroblastoma by counterelectrophoresis usi...

background: national surveys in india have documented an increasing number of adolescent girls suffering from anemia. efforts to build iron stores in adolescent girls will help them improve their prepregnancy hemoglobin level. to assess the effectiveness of school-based supervised weekly, bi–weekly, and daily regimen of iron folic tablets in the treatment of anemia among adolescent girls. metho...

background: major beta thalassemia is the most common inherited anemia with high prevalence in iran and hearing loss is one of its side effects. the present study aimed to determine the hearing status of patients with major thalassemia and its relationship with serum ferritin level, period of blood transfusion and dessfroxamin administration. methods: this descriptive-analytic study was perform...

AIM To investigate the relationship between ferritin and steatosis in patients with chronically abnormal liver function tests (LFTs) and high ferritin level. METHODS One hundred and twenty-four consecutive patients with hyperferritinemia (male > 300 ng/mL, female > 200 ng/mL) were evaluated; clinical, biochemical and serological data, iron status parameters, HFE gene mutations and homeostasis...

Oxidative stress is a major contributor to kidney injury following ischemia reperfusion. Ferritin, a highly conserved iron-binding protein, is a key protein in the maintenance of cellular iron homeostasis and protection from oxidative stress. Ferritin mitigates oxidant stress by sequestering iron and preventing its participation in reactions that generate reactive oxygen species. Ferritin is co...

Introduction: Nowadays one of the most important problems of Thalassemia major patients is the additional load of iron and hemosiderosis, the most important consequence of which is deposited iron in myocardial tissue and the incidence of cardiomyopathy caused by hemochromatosis. The aim of this study was to determine the effect of concurrent (resistance-endurance) exercise on NT-pro BNP and...