BACKGROUND Chronic or recurrent pain associated with the female reproductive system is not well understood and has been neglected in research, despite it being a costly health problem. AIMS The present research investigated the psychosocial impact of vulval pain on health-related quality of life, sexual well-being, and relationship satisfaction among Australian women. METHODS Between June a...

The incidence and mortality rates from endometrial cancer are increasing. There have been no new drugs approved for the treatment of endometrial cancer in decades. The National Cancer Institute, Gynecologic Cancer Steering Committee identified the integration of molecular and/or histologic stratification into endometrial cancer management as a top strategic priority. Based on this, they convene...

Endometrial cancer (EC) is the most common gynecologic malignancy. MicroRNAs (miRNAs) were recently associated with carcinogenesis and progression of EC. In this review, we discuss recent advances and the emerging role of miRNAs in EC and their clinical implications, with special emphasis on the differences between deregulated miRNAs in type I and type II EC, as well as the impact of this dysre...

Mice which are heterozygous for two complementary lethal t mutations (t6/tw32) exhibit complete male sterility. Experiments have been conducted to determine if spermatozoa from these heterozygous males can fertilize oviducal ova in vitro. The experiments have been designed so that specific barriers which are present during in vivo fertilization can be sequentially removed and the fertilizing ab...

Recruitment overfishing (the reduction of a spawning stock past a point at which the stock can no longer replenish itself) is a common problem which can lead to a rapid and irreversible fishery collapse. Averting this disaster requires maintaining a sufficient spawning population to buffer stochastic fluctuations in recruitment of heavily harvested stocks. Optimal strategies for managing spawne...

Erratum The original article [1], was published with the incorrect title " Response to comment on: Gleicher N et al., 2016. Reprod biol endocrinol Sep 5;14(1):54 ". The title of this article should read " Comment on: Gleicher N et al., 2016. Reprod biol endocrinol Sep 5;14(1):54 " and has now also been corrected online. permits unrestricted use, distribution, and reproduction in any medium, pro...

A brief description of the basic pattern of mammalian organogenesis of the female reproductive tract is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather its organization and timing. Tables of comparative development provide a comparison of similar events between man, rat, mouse, and chick.

The majority of new HIV-1 infections are transmitted sexually by penetrating the mucosal barrier to infect target cells. The development of microbicides to restrain heterosexual HIV-1 transmission in the past two decades has proven to be a challenging endeavor. Therefore, better understanding of the tissue environment in the female reproductive tract may assist in the development of the next ge...

For many years it was thought that the female reproductive tract was a sterile environment, devoid of immune cells or pathogens. We now know that the immune system represents an important component of reproductive tissues, influencing many of its biological functions. Similarly, bacteria are present within the female reproductive tract as a normal component. Therefore, the female reproductive t...