Introduction: Hereditary disease discovery and pattern recognition are normally obtained through a large-scale and detailed family health history. However, it is difficult to obtain a large scale, well-orchestrated family health history. Here we try a new method for hereditary disease and pattern discovery without obtaining family health history. Background and Rationale: Columbia Presbyterian ...

conclusions vaccination of non-immune individuals against hav infection in high risk groups especially hemophilia and thalassemia patients is recommended. results did not show any differences about seroprevalence of hev among iranian general population. results anti-hav igg antibodies were observed more frequently in thalassemia patients (60/64; 93.8%) than in hemophilia patients (104/155; 67.1...

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Hemophilia B (also known as Christmas disease) is due to deficiency of coagulation factor IX (FIX). In this issue of the Journal, Nathwani et al. report the first unequivocal evidence of successful gene therapy for hemophilia B — a major advance in this field.1 This success for hemophilia may translate into gene therapy for other blood protein deficiencies. Hemophilia is due to deficiency in a ...

background: pain and limited range of motion (rom) are the crucial subsequent results of joint hemorrhages in individuals with bleeding disorders and hemophilia. exercise interventions are particularly recommended in treatment of such patients. the purpose of this study was to detect the influences of conventional exercise therapy and hydrotherapy on the knee joint complications in patients wit...

As hemophilia is a chronic bleeding diseaseand can interfere with daily performanceof children, these children require continuoustraining to prevent bleeding and take timely action(1). Since children nurses play an important role inthe education of involved children and their Selfefficacyand also due to today’s approach whichis using educational computer games, the use ofeducational games in re...

Background: Hemophilia is a chronic bleeding disease and can interfere with daily performance of children. These children require continuous training to prevent bleeding. Since children nurses play an important role in the education of sick children and their self-efficacy and the increase use of educational computer games, the use of educational games for teaching self-efficacy to children wit...