BACKGROUND Sarcoidosis is a chronic inflammatory disease of unknown etiology, which can involve different organs and systems. Accordingly, sarcoidosis can mimic breast cancer, making the differential diagnosis very difficult. CASE REPORT 5 patients with a diagnosis of both sarcoidosis and breast cancer followed by the Rabin Medical Center between January 1993 and June 2012 were enrolled in th...

BACKGROUND Selected patients with cardiac sarcoidosis undergo heart transplantation, but outcomes may be adversely affected by recurrent cardiac sarcoidosis or progressive extra-cardiac sarcoidosis. OBJECTIVES We present our single-center experience of patients with cardiac sarcoidosis who underwent heart transplantation. METHODS Consecutive patients that underwent heart transplantation bet...

sarcoidosis is a systemic disease that is characterized with noncaseating granulomatous nodules which present in multiple organs specially lungs (90%) . incidence of masses due to sarcoidosis in upper extremity is low and most cases present in association with involvement of pulmonary hilary lymph nodes. in this article we present a rare case of sarcoidosis which presented as a single soft tiss...

Sarcoidosis is a systemic inflammatory disease characterized by the development of noncaseating granulomas in multiple organ systems. Many hematologic malignancies and solid tumors, including melanoma, have been associated with sarcoidosis. We describe the clinical and pathologic findings of a 54-year-old man with melanoma-associated sarcoidosis. In addition, we not only review the literature d...

Dear Editor, The article by Ji et al1 is very interesting. However, they do not mention the increased risk for systemic malignancies especially cutaneous malignancies in patients with sarcoidosis. The incidence of malignancies in patients with sarcoidosis is almost 1.65 times the incidence in patients without any clinical sarcoidosis.2 In fact, patients with sarcoidosis are almost 3 times more ...

Blau syndrome (BS) is a rare autosomal dominant, inflammatory syndrome that is characterized by the clinical triad of granulomatous dermatitis, symmetric arthritis, and recurrent uveitis. Mutations in the nucleotide oligomerization domain 2 (NOD2) gene are responsible for causing BS. To date, up to 30 Blau-associated genetic mutations have been identified within this gene. We report a novel NOD...

we describe a 40-year-old woman presenting with headache, nausea, episodic amnesia and blurred optic disc. brain mri disclosed diffuse leptomeningeal enhancement. csf analysis showed aseptic meningitis with elevated ace level. neurosarcoidosis was diagnosed based on granulomatosis changes on tissue biopsy.

The pulse wave velocity (PWV), as an indicator of arterial distensibility, may play an important role in the stratification of patients based on the cardiovascular risk. PWV inversely correlates with arterial distensibility and relative arterial compliance. Decreased arterial distensibility alters arterial blood pressure and flow dynamics, and disturbes coronary perfusion. Systemic immune and i...

Uveitis is often a manifestation of sarcoidosis. Less well-recognized, however, is the development of uveitis several years before the diagnosis of systemic sarcoidosis. The possibility that presentation of uveitis is a marker for the chronicity of sarcoidosis has never been investigated. The aim of this work was to evaluate, in a Caucasian population, the epidemiology of uveitis as the primary...

PURPOSE Many studies include elevated activity of angiotensin-converting enzyme (ACE) in serum in sarcoidosis and in ocular sarcoidosis as well, but there are only a few analyzing ACE activities in aqueous humor. The aim of this study is to illuminate the diagnostic value of ACE in aqueous humor in patients with ocular sarcoidosis. METHODS We analyzed twenty patients with ocular sarcoidosis a...