Glioblastoma differ from many other tumors in the sense that they grow infiltratively into the brain tissue instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly. In contrast, brain tissue infiltrated by tumor cells at low density appears normal on current imaging modalities. In current cl...

Gorlin-Goltz syndrome or basal cell nevus syndrome is an autosomal dominant syndrome characterized by skeletal anomalies, numerous cysts observed in the jaw, and multiple basal cell carcinoma of the skin, which may be accompanied by falx cerebri calcification. Basal cell carcinoma is the most commonly skin tumor with slow clinical course and low metastatic potential. Its concomitance with Gorli...

Interhemispheric hyperdensity or unenhanced computed tomography was originally considered a sign of subarachnoid hemorrhage, the "falx sign." It has since been identified as a normal feature and has also been seen with interhemispheric subdural hemorrhage. To determine the differential features of interhemispheric hemorrhage, 50 patients with subarachnoid hemorrhage and 32 patients with interhe...

BACKGROUND AND PURPOSE Few reports have documented signal abnormalities within the corpus callosum on MR studies obtained after ventricular decompression in patients with hydrocephalus. Our purpose was to establish the frequency of this finding in shunted patients and attempt to elucidate its cause and clinical significance. METHODS All patients with hydrocephalus shunted between 1989 and 199...

Primary intracranial neoplasms rarely give rise to distant extracranial metastases despite the fact that many of them possess the other attributes of malignant neoplasms. Paradoxically it appears that extra-cranial metastases are more liable to originate from the less rather than the more malignant primaryintra-cranial neoplasms (Russell and Rubinstein, 1963). Cushing and Eisenhardt (1938) repo...

Hemangiopericytoma (HPC) is a rare vascular tumor that originates from the pericytes of blood vessels. HPC has a propensity for metastasis and is frequently aggressive. HPC can grow rapidly and usually occurs in the base of the skull, falx, tentorium, or nearby sinus, but occurs in the spinal canal less frequently. Peripheral nerve tissue can be compressed by HPC, causing corresponding signs an...

Gorlin's syndrome, also known as multiple basal cell naevi syndrome, is a well documented disorder of unknown etiology. Very often it is familial of autosomal dominant mode of transmission. It can affect any age group of both sexes. rt presents a wide spectrum of signs and symptoms involving nearly every system of the body. Classically it consists of triad features of multiple basal cell naevi,...

Gorlin-Goltz syndrome is a rare autosomal dominant disorder that involves multiple organ systems, including the skin, skeleton and jaws. We report a case of young female with multiple odontogenic keratocysts, high arched palate, euryopia, palmer pits, solitary, pigmented nevus , areas of hyper-pigmentation in the upper eyelid of left eye, dorsal surface of hands, calcified diaphragma sellae, ri...