Objective: To report an aggressive case of extranodal natural killer/T-cell lymphoma (NKTCL) of the ethmoid sinus presenting as orbital cellulitis Method: Case report Results: A 56-year-old male presented with right eye redness, reduced vision, and periorbital swelling for 5 weeks duration associated with a two-month history of blocked nose. The visual acuity of the right eye was 6/18. The eye ...

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an extranodal lymphoma composed of morphologically heterogeneous small B-cells including marginal zone (centrocyte-like) cells, cells resembling monocytoid cells, small lymphocytes, and scattered immunoblasts and centroblast-like cells. There is plasma cell differentiation in a proportion of the cases. The...

Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL) are the malignant neoplasm spectrum originating from the lymphoid system and constituting 8% of all malignancies. Although, both are known as primary malignancies of lymph nodes, extranodal involvement can be seen. In this case presentation, in addition to nodal and bone involvement areas in a patient diagnosed as marginal zone lymphoma, rare...

Nasal type extranodal natural killer (NK) NK-cell/T-cell lymphoma (NKTCL) is a rare extranodal lymphoma of NK-cell or T-cell origin that most commonly affects immunocompetent middle-aged men of Asian or Native American descent [1]. The pathogenesis is not understood completely, but it is related in part to infection of the tumor cells with Epstein-Barr virus (EBV) [2]. Around 6-7% of all non-Ho...

Angioimmunoblastic T-cell lymphoma (AITL) is a frequent subtype of peripheral T – cell lymphoma (PTCL) characterized by generalized lymphadenopathy, hepatosplenomegaly, and frequent B symptoms. Extranodal manifestations are quite common in this subtype of Non Hodgkins Lymphoma which is characterized by frequent skin involvement. However, the extranodal disease should be evaluated thoroughly and...

Anaplastic large cell lymphoma (ALCL) is a CD30-positive neoplasm of either T-cell or null-cell lineage accounting for 2% to 8% of all lymphomas.1 Most frequently, patients with ALCL present with advanced disease with extranodal involvement.2 The central nervous system (CNS) (30%), gastrointestinal tract (25%), and bone marrow are the most commonly involved extranodal sites.3 Cases of ALCL with...

Diffuse large B cell lymphoma (DLBCL) is the most common histologic subtype of Non-Hodgkin’s lymphoma (NHL), accounting for approximately twenty five percent of cases. Forty percent of patients with DLBCL present with the primary lesion in an extranodal site. The gastrointestinal tract is the most frequent site of extranodal lymphoma, with the stomach and intestines most often involved. Involve...

Extranodal natural killer cell (NK) T lymphoma (ENKL) is a rare type of non Hodgkins lymphoma, accounting for 5% 10% total NHL cases.