OBJECTIVES To conduct an exploration of the hospital costs of extracorporeal life support therapy. Extracorporeal life support seems an efficient therapy for acute, potentially reversible cardiac or respiratory failure, when conventional therapy has been inadequate, or as bridge to transplant, but unfortunately, no evidence in randomized controlled trials is delivered yet. DESIGN Single-cente...

OBJECTIVES To describe functional status at hospital discharge for neonatal and pediatric patients treated with extracorporeal membrane oxygenation, and identify factors associated with functional status and mortality. DESIGN Secondary analysis of observational data collected by the Collaborative Pediatric Critical Care Research Network between December 2012 and September 2014. SETTING Eigh...

respiratory failure is a serious complication of h1n1 influenza that, if not properly managed, can cause death. when mechanical ventilation is not effective, the only way to save the patient’s life is extracorporeal membrane oxygenation (ecmo). a prolonged type of cardiopulmonary bypass, ecmo is a high-cost management modality compared to other conventional types and its maintenance requires sk...

OBJECTIVE Extracorporeal membrane oxygenation as a bridge to lung transplantation has traditionally been associated with substantial morbidity and mortality. A major contributor to these complications may be weakness and overall deconditioning secondary to pretransplant critical illness and immobility. In an attempt to address this issue, we developed a collaborative program to allow for active...

Background—Extracorporeal circulation induces a systemic inflammatory response, which may adversely affect organ function. One manifestation of this response is increased fibrinolysis. Antifibrinolytic drugs such as aprotinin and e-aminocaproic acid have been effective in reducing fibrinolysis and blood loss after extracorporeal circulation; however, the effects of antifibrinolytic drugs on pro...

Background and Objective: Extracorporeal membrane oxygenation (ECMO) may be used as a substitute of traditional cardiopulmonary bypass (CPB) in thoracic surgeries. Extended resections for the treatment non-small cell lung cancer (NSCLC) occasionally require extracorporeal life support. We present narrative review current clinical uses devices this setting patients.

With advances in mechanical circulation, venoarterial extracorporeal membrane oxygenation has become an established technique to provide cardiopulmonary support for patients with cardiovascular collapse. This article reviews the physiological principles of such extracorporeal technique and its interaction with the native heart. Practical aspects including equipment, patient selection, and commo...

This paper presents a novel method to predict the occlusion of a withdrawing cannula during extracorporeal circulation due to a networked intensive care setup. During in-vivo experiments we were able to detect the cannula suction up to 90 seconds prior to the collapse of extracorporeal blood flow. The elaborated metric is based on heart rate, extracorporeal blood flow and blood pressure at the ...

OBJECTIVES Lung transplantation for idiopathic pulmonary arterial hypertension has the highest reported postoperative mortality of all indications. Reasons lie in the complexity of treatment of these patients and the frequent occurrence of postoperative left ventricular failure. Transplantation on intraoperative extracorporeal membrane oxygenation support instead of cardiopulmonary bypass and e...