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We show that drought-induced changes in the intensity of riots lead to moves towards democracy in sub-Saharan Africa, and that these changes are often a result of concessions made as a result of the riots. This provides evidence that low-intensity conflict can have a substantial short-run impact on democratic change, and supports the “window of opportunity” hypothesis: droughts lead to an incre...

We engineered a photoactivatable system for rapidly and reversibly exporting proteins from the nucleus by embedding a nuclear export signal in the LOV2 domain from phototropin 1. Fusing the chromatin modifier Bre1 to the photoswitch, we achieved light-dependent control of histone H2B monoubiquitylation in yeast, revealing fast turnover of the ubiquitin mark. Moreover, this inducible system allo...

This paper addresses the problem of guaranteed delivery of messages with hard deadlines in a DQDB network. We present a cyclic reservation scheme capable of allocating bandwidth with any arbitrary granular-ity and provide deterministic delay guarantees. We propose two implementations of the allocation scheme within the framework of DQDB medium access control protocol. The proposed implementatio...

This paper provides a direct test of how fixed export costs and productivity jointly determine firm-level export behavior. Using Chilean data, we construct indices of fixed export costs for each industry-region-year triplet and match them to domestic firms. Our empirical results show that firms facing higher fixed export costs are less likely to export, while those with higher productivity expo...

The mRNA nuclear export receptor Mex67/Mtr2 is recruited to mRNAs through RNA-binding adaptors, including components of the THO/TREX complex that couple transcription to mRNA export. Here we show that the ubiquitin-associated (UBA) domain of Mex67 is not only required for proper nuclear export of mRNA but also contributes to recruitment of Mex67 to transcribing genes. Our results reveal that th...

The Prospero transcription factor promotes neural differentiation in Drosophila, and its activity is tightly regulated by modulating its subcellular localization. Prospero is exported from the nucleus of neural precursors but imported into the nucleus of daughter cells, which is necessary for their proper differentiation. Prospero has a highly divergent putative homeodomain adjacent to a conser...

This study examines the impact that various incentives to export have on the export marketing performance of Australian export market ventures. The incentives to export used in this study were adapted from Sullivan and Bauerschmidt (1990). The unit of analysis was Australian export market ventures engaged in exporting to foreign markets. Data were gathered via a self-administered mail survey di...

Strambio-De-Castilla, Caterina, "Jumping over the fence: RNA nuclear export revisited" (2013).

Health care processes are nowadays heavily dependent on Information Technology (IT). On the other side, assessing a higher quality of health care to patients has become increasingly important. Effective health care processes are thereby heavily dependent on a comprehensive IT-support. Therefore, a thorough understanding about both the hospital IT-systems and clinical pathways is required, to id...